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ProteomicsMass spectrometry-guided molecular modeling predicts the interaction interface for a camelid single-domain antibody targeting the Plasmodium falciparum circumsporozoite protein’s C-terminal domain
To improve malaria diagnostics novel detector systems with high specificity and sensitivity are required. The malarial antigen PfCSP-Cext was selected to generate the camelid single domain antibody sdAbCSP1, which is intended to be used as capture device for detecting PfCSP-Cext in serum of acutely ...
ORGANISM(S): Lama 
2024-08-28 | PXD051302 | Pride
Online nanolc esi-mse  item-two Offline nanoesi-mse 
ProteomicsExploring Top-Down Mass Spectrometric Approaches To Probe Forest Cobra (Naja melanoleuca) Venom Proteoforms
Three main top-down mass spectrometry methodologies were employed in a proof-of-concept study to characterise selected three finger toxins and phospholipase A2 toxins from the forest cobra (Naja melanoleuca) venom. The novel utility of data-independent acquisition, alternative hybrid ECD-CID fragmen...
ORGANISM(S): Naja melanoleuca 
2024-09-05 | PXD052561 | Pride
Ecd-cid fragmentation Proteoforms Top-down proteomics Cyclic ion mobility Snake venom Data-independent acquisition 
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