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TranscriptomicsFyn-dependent prefrontal cortex gene networks in acute ethanol sensitivity
Fyn kinase has been implicated in multiple behavioral responses to ethanol and in the regulation of myelin gene expression. Here we tested whether Fyn kinase modulated basal or ethanol-responsive expression of genes regulated by acute ethanol in brain regions of the mesolimbocortical dopamine pathwa...
ORGANISM(S): Mus musculus 
2014-08-31 | E-GEOD-49028 | biostudies-arrayexpress
TranscriptomicsFunction of Periplasmic Hydrogenases in the Sulfate-Reducing Bacterium Desulfovibrio vulgaris Hildenborough
The sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough possesses four periplasmic hydrogenases to facilitate the oxidation of molecular hydrogen. These include an [Fe], a [NiFeSe] and two [NiFe] hydrogenases encoded by the hyd, hys, hyn1 and hyn2 genes, respectively. In order to underst...
ORGANISM(S): Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough 
2010-06-10 | E-GEOD-8137 | biostudies-arrayexpress
UnknownA fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS.
Not available
S-EPMC9928052 | biostudies-literature
UnknownAddendum: Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
Not available
S-EPMC10208202 | biostudies-literature
UnknownSystems vaccinology of the BNT162b2 mRNA vaccine in humans.
Not available
S-EPMC8761119 | biostudies-literature
UnknownSystems biological assessment of human immunity to BNT162b2 mRNA vaccination.
Not available
S-EPMC8132234 | biostudies-literature
TranscriptomicsYeast m6A methylated mRNAs are enriched on translating ribosomes during meiosis, and under Rapamycin treatment
Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the recent finding of FTO?s (Fat Mass Obesity) N6-methyl-adenosine (m6A) deaminase activity, thus suggested a link between obesity-associated diseases and the presence of m6A...
ORGANISM(S): Saccharomyces cerevisiae SK1 
2015-08-12 | E-GEOD-68435 | biostudies-arrayexpress
TranscriptomicsThe Brucella abortus virulence regulator, LovhK, is a sensor kinase in the general stress response signaling pathway
We sequenced the transcriptomes of B. abortus 2308 wild type, rpoE1, and lovhK deletion strains to assess gene expression in response to oxidative stress. The data represent 2 independent biological replicates of each strain. Illumina RNA-seq of total mRNA isolated from wild type, rpoE1, and lovhK d...
ORGANISM(S): Brucella melitensis 
2014-09-25 | E-GEOD-59513 | biostudies-arrayexpress
UnknownMass cytometry analysis of blood from peanut-sensitized tolerant and clinically allergic infants.
Not available
S-EPMC9715645 | biostudies-literature
MetabolomicsMetabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

Breast cancer metastasis occurs via blood and lymphatic vessels. Breast cancer cells 'educate' lymphatic endothelial cells (LECs) to support tumor vascularization and growth. However, despite known metabolic alterations in breast cancer, it remains unclear how lymphatic endothelial cell metabolis...

2024-06-25 | MTBLS859 | MetaboLights
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