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TranscriptomicsMonocyte derived macrophages treated with lysophosphatidic acid
Peripheral blood monocytes were differentiated into macrophages, starved for 24h hours, and treated for 3h with LPA 18:0, 20:4 or a mix of LPAs similar to the composition in ascites (1 µM 16:0 + 0.25 µm 18:0 + 0.5 µM 18:1 + 1.625 µM 18:2 + 1.625 µM 20:4). RNA expression was measured via QuantSeq.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-13993 | biostudies-arrayexpress
ProteomicsIdentification of phosphorylation sites regulated by lysophosphatidic acid (LPA) in OCMI91s ovarian cancer cells
Elevated levels of lysophosphatidic acid (LPA) species accumulate in the ascites of ovarian high grade serous cancer (HGSC) and are associated with a short relapse-free survival. LPA is known to support the metastatic spread of cancer cells by activating a multitude of signaling pathways through G-p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-25 | MSV000091146 | MassIVE
ProteomicsIdentification of phosphorylation sites regulated by lysophosphatidic acid (LPA) in OVCAR8 ovarian cancer cells
Elevated levels of lysophosphatidic acid (LPA) species accumulate in the ascites of ovarian high grade serous cancer (HGSC) and are associated with a short relapse-free survival. LPA is known to support the metastatic spread of cancer cells by activating a multitude of signaling pathways through G-p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-26 | MSV000091158 | MassIVE
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