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TranscriptomicsExpression data from cumulus cells from C57Bl/6 and Ptger2 (EP2) KO mice
To understand the role of prostaglandin (PG) receptor EP2 (Ptger2) signaling in ovulation and fertilization, we investigated time-dependent expression profiles in wild-type (WT) and Ptger2-/- cumuli before and after ovulation by using microarrays. We used Affymetrix U74A ver2 microarrays to investig...
ORGANISM(S): Mus musculus 
2010-03-02 | E-GEOD-20439 | biostudies-arrayexpress
TranscriptomicsIdentification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model
More effective therapeutic approaches for castration-resistant prostate cancer (CRPC) are urgently needed, thus reinforcing the need to understand how prostate tumors progress to castration resistance. We have established a novel mouse xenograft model of prostate cancer, KUCaP-2, which expresses the...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-21887 | biostudies-arrayexpress
ProteomicsGNA13 – peptide interaction analysis (GST-tag co-purification)
Alpha-1-antitrypsin (AAT), a circulating serine protease inhibitor, is an acute inflammatory response protein with anti-inflammatory functions. The C-terminal peptides of AAT are found in various tissues and have been proposed as putative bioactive peptides with multiple functions, but its mechanism...
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2025-01-01 | PXD054789 | JPOST Repository
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