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Previous work has shown that a series of honey bee brain proteins were probably linked to the proboscis extension reflex (PER) , a model studying insect behaviour. Herein, it was the aim of the study to generate a “synaptic proteome” and to investigate which proteins were paralleling olfactory cond...
ORGANISM(S): Apis mellifera (Honeybee) 
2019-05-27 | PXD011217 | Pride
Specific genes or encoded proteins are involved in regulating various learning models of different species through certain signaling pathways,but whether there are also regulatory genes during bimodal learning and memory is largely unknown. Using a multi-omics approach to examine gene expression cha...
ORGANISM(S): Apis mellifera (Honeybee) 
2021-09-13 | PXD017008 | Pride
Here we used double-transgenic amyloid precursor protein/presenilin 1 (APPswe/PS1dE9) mice and label-free quantitative proteomics to analyze potential early pathological effects on the olfactory bulb (OB) during AD progression.
ORGANISM(S): Mus musculus (Mouse) 
2016-08-09 | PXD003683 | Pride
Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster
Neurotoxicity of formaldehyde (FA) in the human health attracted intensive studies Long-term exposure to FA leads to learning and memory decline and is responsible for the multiple chemical sensitivity (MCS) or sick building syndrome (SBS). It was cleared that Formaldehyde impairs Learning and Memor...
ORGANISM(S): Mus musculus 
The polyamines putrescine, spermidine and spermine are ubiquitous metabolites synthesized in all cells. The intracellular levels of polyamines, especially spermidine, decrease in aging. Oral spermidine supplementation has been reported to alleviate aspects of aging-related disease in animal models, ...
ORGANISM(S): Drosophila melanogaster 
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