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ProteomicsPurification, Structural Characterization, and Anticandidal Activity of a Chitin-binding Peptide with high Similarity to Hevein and Endochitinase Isolated from Pepper Seeds
Antimicrobial peptides (AMPs) are a group of molecules that occur naturally in all living organisms and help them to defend against various pathogens, including fungi, bacteria and viruses (Gan et al., 2021). AMPs have a low molecular mass (~2-50 amino acids), are rich in hydrophobic amino acids and...
ORGANISM(S): Capsicum chinense 
2024-10-17 | PXD054607 | Pride
Antimicrobial peptides  capsicum chinense  fungi  candida albicans  c. tropicalis 
ProteomicsMass spectrometry analysis of the Skp1 and Cullin1 interactome in Leishmania infantum
Leishmania infantum is the causative agent of visceral leishmaniasis in Latin America, a lethal disease if misdiagnosed or left untreated. The ubiquitin proteasome system (UPS) is the main regulator of intracellular proteolysis in eukaryotes and is required for parasite's to life cycle and infectio...
ORGANISM(S): Leishmania infantum 
2024-07-01 | PXD051961 | Pride
Ap-ms Cullin-1-ring ubiquitin ligases (crl1) E3 ubiquitin ligases Leishmania infantum 
ProteomicsThe pterocarpan (+)-PTC mimics microtubule-destabilizing agents by modulating cytoskeletal proteins in metastatic castration-resistant prostate cancer: a proteomic perspective
Treatment of metastatic castration-resistant prostate cancer (mCRPC) remains clinically challenging due to tumor heterogeneity and drug resistance. Microtubule-targeting agents are a mainstay of mCRPC therapy, but limitations persist regarding progression-free survival. Pterocarpans have emerged as ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD073655 | Pride
Prostate cancer Proteomics Cytoskeleton proteins Pterocarpans Microtubule-targeting agents 
MetabolomicsGlobal Analyses of Selective Insulin Resistance in Hepatocytes due to Palmitate Lipotoxicity
Obesity is tightly linked to hepatic steatosis and insulin resistance. One feature of this association is the paradox of selective insulin resistance: insulin fails to suppress hepatic gluconeogenesis but activates lipid synthesis in the liver. How lipid accumulation interferes selectively with some...
2018-04-26 | MTBLS582 | MetaboLights
UnknownRenewing Felsenstein's phylogenetic bootstrap in the era of big data.
Not available
S-EPMC6030568 | biostudies-literature
UnknownAntiviral and Immunomodulatory Effects of 7-Deaza-2-methyladenosine (7DMA) in a Susceptible Mouse Model of Usutu Virus Infection.
Not available
S-EPMC12737359 | biostudies-literature
UnknownInulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.
Not available
S-EPMC10131329 | biostudies-literature
UnknownA hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp.
Not available
S-EPMC6797224 | biostudies-literature
UnknownEcological mechanisms explaining interactions within plant-hummingbird networks: morphological matching increases towards lower latitudes.
Not available
S-EPMC7126064 | biostudies-literature
UnknownHigh proportion of smaller ranged hummingbird species coincides with ecological specialization across the Americas.
Not available
S-EPMC4760165 | biostudies-literature
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