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TranscriptomicsTrancriptome analysis of peripheral leukocytes from SARS-CoV-2 infected patients and healthy uninfected individuals during the first wave of COVID-19 pandemic in Brazil
To evaluate the gene expression profiling of peripheral leukocytes in different outcomes of SARS-CoV-2 infections, whole blood samples were collected from individuals with positive SARS-CoV-2 nasopharyngeal swab by RT-PCR (54 patients) and healthy uninfected individuals (12 volunteers). Infected pat...
ORGANISM(S): Homo sapiens 
2022-04-29 | E-MTAB-11240 | biostudies-arrayexpress
TranscriptomicsBulk mRNA-seq of blood samples of visceral leishmaniasis patients during active disease and after treatment (cured), asymptomatic individuals and healthy uninfected control volunteers.
To ascertain which genes are involved in the outcome of Leishmania infantum infections and immunopathology of human visceral leishmaniasis (VL), we investigated the transcriptional profile of whole blood samples from patients during active VL compared to the same patients 180 days after being treate...
ORGANISM(S): Homo sapiens 
2022-03-10 | E-MTAB-11047 | biostudies-arrayexpress
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes β-Cell Proliferation [10 days]
Obesity is associated with an increase in β-cell mass in response to the rising demand for insulin. β-cell plasticity is essential to maintaining glucose homeostasis, however, the cellular and molecular mechanisms by which β-cell mass is regulated remain poorly understood. Recently, we described the...
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44045 | biostudies-arrayexpress
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes ?-Cell Proliferation [30 days]
Obesity is associated with an increase in ?-cell mass in response to the rising demand for insulin. ?-cell plasticity is essential to maintaining glucose homeostasis, however, the cellular and molecular mechanisms by which ?-cell mass is regulated remain poorly understood. Recently, we described the...
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44046 | biostudies-arrayexpress
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes ?-Cell Proliferation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44047 | biostudies-arrayexpress
TranscriptomicsTemporal bovine liver gene expression
Liver from five Holstein cows fed to current National Research Council (2001) recommendations during the dry period and early lactation was biopsied at -65, -30, -14, 1, 14, 28, and 49 days relative to parturition. cDNA from liver and a reference standard (made from cattle tissues not including liv...
ORGANISM(S): Bos taurus 
2010-06-09 | E-GEOD-2692 | biostudies-arrayexpress
TranscriptomicsImmunity and Defense Genes in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis patients
Large-scale gene expression profiling of peripheral blood mononuclear cells from Rheumatoid Arthritis (RA) patients could provide a molecular description that reflects the contribution of diverse cellular responses associated with this disease. The aim of our study is to identify peripheral blood ge...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-15573 | biostudies-arrayexpress
ProteomicsCharacterization of the secretome of glial cells exposed to glioblastoma secreted factors
Glioblastoma (GBM), the most malignant primary brain tumor, is characterized by widespread heterogeneity, leading to poor and unpredictable clinical outcomes. Recent studies have provided evidences that the tumor microenvironment has a critical role in regulating tumor growth by establishing a compl...
ORGANISM(S): Mus musculus (Mouse) 
2017-10-09 | PXD006007 | Pride
Glial cells  gliobastome  secretome  swath-ms 
ProteomicsAdaptive mechanisms of Aspergillus fumigatus’conidia to nutrient restriction
Aspergillus fumigatus, a common airborne fungus, has been reported as one of the most frequent agents of human fungal infections. However, A. fumigatus conidia atmospheric resistance and longevity, and their aging mechanism are unknown. Therefore, the main purpose of this work is to clarify the main...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) 
2017-04-04 | PXD003355 | Pride
Proteomics changes  aspergillus fumigatus’conidia  swath-ms  acetylation 
UnknownAntiviral activity of ouabain against a Brazilian Zika virus strain.
Not available
S-EPMC9308787 | biostudies-literature
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