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TranscriptomicsTranscription profiling of mouse Th1 and Th17 T helper cells
This is to compare the gene expression profile of Th1 and Th17 cells. Experiment Overall Design: Two replicates (rep1, rep2) in two groups (Th1, Th17).
ORGANISM(S): Mus musculus 
2009-01-31 | E-GEOD-14026 | biostudies-arrayexpress
TranscriptomicsComparative Validation of the D. melanogaster Encyclopedia of DNA Elements Transcript Models
The model organism Encyclopedia of DNA Elements project (modENCODE) has produced a comprehensive annotation of D. melanogaster transcript models based on an enormous amount of high-throughput experimental data. However, some transcribed elements may not be functional, and technical artifacts may lea...
ORGANISM(S): Drosophila ficusphila 
2013-02-25 | E-GEOD-44612 | biostudies-arrayexpress
TranscriptomicsIdentification of IL-22 regulated genes in the ileum after infection with Toxoplasma gondii
IL-22 acts on epithelial cells and has been shown to induce tissue protective and wound healing responses in these cells. But it has recently been decribed that IL-22 exacerbates ileatis after infection with T. gondii. The goal of the study is to identify the IL-22-dependent genes during T. gondii i...
ORGANISM(S): Mus musculus 
2015-01-31 | E-GEOD-65472 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gonads from E14.5 megalin+/+ and megalin-/- embryos
Presently, genes regulated by steroid hormones during induced regression of the CSL (cranial suspensory ligament) are unknown. To identify such genes and to evaluate their expression levels in megalin-deficient mice, we performed global gene expression profiling on gonads from E14.5 megalin+/+ and m...
ORGANISM(S): Mus musculus 
2005-06-30 | E-MEXP-352 | biostudies-arrayexpress
UnknownThe impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
Not available
S-EPMC8552693 | biostudies-literature
TranscriptomicsHypoxia response in C. neoformans in H99, CM092 and CM098
(1) The identification of genes that are transcriptionally regulated in response to exposure to hypoxia (~0.2% oxygen) in H99 (WT) and strains CM092 and CM098. (2) The identification of genes that are differentially-regulated in the strain CM093 compared to H99 (WT) Keywords: hypoxia response, compa...
ORGANISM(S): Filobasidiella neoformans 
2010-06-12 | E-GEOD-6226 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection
Salmonella enterica serovar Typhimurium (S. typhimurium) bacteria cause an inflammatory and lethal infection in zebrafish embryos. To characterize the embryonic innate host response at the transcriptome level, we have extended and validated previous microarray data by Illumina next-generation sequen...
ORGANISM(S): Danio rerio 
2010-10-25 | E-GEOD-22472 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of whole adult females and males, and miixed sex embryos, from multiple Drosophila species
We performed transcriptional profiling of sexed whole adults and mixed sex embryos of eight Drosophila species. These data were used in a comparative transcriptomics analysis of multiple Drosophila species to define functional elements conserved throughout the Drosophila genus. For each species, wi...
ORGANISM(S): Drosophila rhopaloa 
2013-02-22 | E-GEOD-43321 | biostudies-arrayexpress
TranscriptomicsAnalysis of mRNA expression differences in the skin of Casp-8F/–K5-Cre and Casp-8F/+K5-Cre mice
This SuperSeries is composed of the following subset Series: GSE17344: Analysis of spatial mRNA expression differences in the skin of Casp-8F/–K5-Cre or Casp-8F/+K5-Cre mice GSE17345: Analysis of temporal mRNA expression changes in cultured keratinocytes from Casp-8F/–K5-Cre and Casp-8F/+K5-Cre mice...
ORGANISM(S): Mus musculus 
2009-07-29 | E-GEOD-17365 | biostudies-arrayexpress
TranscriptomicsmRNA sequence data of individual Drosophila melanogaster male and female flies from 16 Drosophila Genetic Reference Panel lines reared in replicated environments
Our primary objective was to characterize the amount of variation in transcript abundance among individual flies with identical genotypes. We also wanted to determine which analysis methods would be optimal for RNA-Seq data. To meet these objectives, we performed transcriptional profiling of whole...
ORGANISM(S): Drosophila melanogaster 
2015-12-21 | E-GEOD-60314 | biostudies-arrayexpress
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