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MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
TranscriptomicsYeast carbon and nitrogen impulse transient data in chemostat
Wild type S. cerevisiae cells were grown under glucose or ammonium limitation in fully controlled aerobic chemostat cultures. At steady state, the limited nutrient was introduced into the growth medium in an impulse like manner to recover the medium to its non-limiting conditions. Samples were colle...
ORGANISM(S): Saccharomyces cerevisiae 
2011-10-03 | E-MTAB-643 | biostudies-arrayexpress
TranscriptomicsYeast drug resistance gene mutants in glucose or ammonium limited chemostats
Homozygous deletion mutants of drug resistance genes QDR3 and PDR3 and the homozygous deletion of HO (control) were grown in ammonium limited or glucose limited synthetic defined medium in aerated, pH controlled chemostats at a dilution rate of 0.1hr-1. Samples were collected at steady state.
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-23 | E-MTAB-707 | biostudies-arrayexpress
TranscriptomicsHif1α down-regulation is associated with transposition of great arteries in mice treated with a RA antagonist
Aims: Congenital heart defect (CHD) account for 25% of all human congenital abnormalities. Very few CHD-causing genes have been identified so far; so, to discover further genes we performed a global transcriptome analysis in mouse models of CHD. Methods and results: By the use of a retinoic acid com...
ORGANISM(S): Mus musculus 
2010-09-20 | E-GEOD-19012 | biostudies-arrayexpress
UnknownExtension of the yeast metabolic model to include iron metabolism and its use to estimate global levels of iron-recruiting enzyme abundance from cofactor requirements.
Not available
S-EPMC6492170 | biostudies-literature
UnknownThe subcellular organisation of Saccharomyces cerevisiae.
Not available
S-EPMC6391909 | biostudies-literature
TranscriptomicsTranscription profiling of yeast cells (homozygous deletion mutants of BY4743) grown in chemostats, sampled at steady state. Glucose and ammonium limitation, dilution rates 0.1 and 0.2 hr-1, gene deletions HO and HAP4 applied
S. cerevisiae cells (homozygous deletion mutants of BY4743) grown in chemostats, sampled at steady state. Glucose and ammonium limitation, dilution rates 0.1 and 0.2 hr-1, gene deletions HO and HAP4 applied.
ORGANISM(S): Saccharomyces cerevisiae 
2005-12-31 | E-MEXP-442 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast grown in gastric or duodenal medium to identify promoters that could be used to down-regulate genes used in the release of therapeutic proteins
The use of yeast as a delivery system is an attractive option for the oral administration of therapeutic agents. We recently developed mutants of Saccharomyces cerevisiae capable of lysis upon conditional down-regulation of the expression of the cell wall genes PKC1 and SRB1. The lysis mechanism of ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-01 | E-MEXP-2127 | biostudies-arrayexpress
MetabolomicsMetabolomics Analysis Reveals Tissue-Specific Metabolite Compositions in Leaf Blade and Traps of Carnivorous Nepenthes Plants
Nepenthes is a genus of carnivorous plants that evolved a pitfall trap, the pitcher, to catch and digest insect prey to obtain additional nutrients. Each pitcher is part of the whole leaf, together with a leaf blade. These two completely different parts of the same organ were studied separately in a...
2020-07-10 | MTBLS1783 | MetaboLights
UnknownGenotypic and physiological characterization of Saccharomyces boulardii, the probiotic strain of Saccharomyces cerevisiae.
Not available
S-EPMC1855594 | biostudies-literature
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