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MetabolomicsMolecular evidence of shipping noise impact on the blue mussel, a key species for the sustainability of coastal marine environments

Anthropogenic oceanic noise due to shipping has increased up to 32-fold over the last five decades, putting marine organisms at risk. While the impact of noise on marine mammals is well documented, its effect on molluscs, which hold immense economic and ecological importance, remain largely unkno...

2025-04-11 | MTBLS5678 | MetaboLights
UnknownProximal tibiofibular stabilization by anatomical ligamentoplasty and diaphyseal osteotomy of the fibula.
Not available
S-EPMC9125725 | biostudies-literature
MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
TranscriptomicsMicroarray expression profiling of NKT and MAIT subsets in different organs of B6-MAIT/CAST mice.
MAIT cells (MAITs) represent an abundant T lymphocyte subset with unique specificity for microbial metabolites presented by the MHC-1b molecule, MR1. MAIT conservation along evolution indicates important, non-redundant functions, but their low frequency in mice has hampered their detailed characteri...
ORGANISM(S): Mus musculus 
2018-12-03 | E-MTAB-7133 | biostudies-arrayexpress
TranscriptomicsRNA-seq expression profiling of humain MAIT cells in blood and liver as compared to mainstream TCD4+ and TCD8+ cells.
At variance with what is observed in mice, no distinct MAIT1 or MAIT17 subsets exist in human blood, as all MAIT cells express a variety of transcription factors such as Rorgt, Tbet, Eomes and Helios. However, they are also found in tissues in which they have specific effector functions. To determin...
ORGANISM(S): Homo sapiens 
2018-12-03 | E-MTAB-7143 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Lactobacillus delbrueckii subsp. delbrueckii during soy juice fermentation.
The objective of this study was to decipher the metabolism expressed by Lactobacillus delbrueckii subsp. delbrueckii CIRM-BIA865 during soy juice fermentation using transcriptomics. The whole genome was sequenced, assembled and annotated. CIRM-BIA865 was then used to ferment soy juice to produce a s...
ORGANISM(S): Lactobacillus delbrueckii 
2023-05-13 | E-MTAB-12095 | biostudies-arrayexpress
UnknownOptimizing Tedizolid Dosing in Cerebral Nocardiosis: Clinical Impact of Direct Unbound Concentration Measurement and Population PK Modelling in Two Cases.
Not available
S-EPMC12852995 | biostudies-literature
TranscriptomicsFermentation of soy juice by Lactiplantibacillus plantarum confers a yogurt-like texture, flavours and health-promoting metabolites
The aim of the study was to decipher metabolisms responsible (i) for the peculiar adaptation of L. plantarum during soy juice fermentation and (ii) for the release of aroma compounds, amino and short-chain fatty acid, and metabolites with health-promoting properties in soy yogurt. The strategy was t...
ORGANISM(S): Lactiplantibacillus plantarum 
2024-08-18 | E-MTAB-14345 | biostudies-arrayexpress
GenomicsA GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus.
Uveal melanoma, a rare malignant tumor of the eye, is predominantly observed in populations of European ancestry. A genome-wide association study of 259 uveal melanoma patients compared to 401 controls all of European ancestry revealed a candidate locus at chromosome 5p15.33 (region rs421284: OR = 1...
EGAS00001002334 | EGA
TranscriptomicsA stemness-related ZEB1-MSRB3 axis governs cellular pliancy and cancer genome stability.
Genomic instability is a prominent driver of tumorigenesis. However, a significant fraction of human cancers display few genomic aberrations, suggesting alternative roads towards malignancy. Here, we show that the differentiation status of normal human mammary epithelial cells influences the early r...
ORGANISM(S): Homo sapiens 
2017-03-23 | E-MTAB-4145 | biostudies-arrayexpress
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