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TranscriptomicsXenopus M-phase extract treated induced pluripotent stem cells
Transfer of somatic cell nuclei to enucleated eggs or ectopic expression of specific transcription factors are two different reprogramming strategies used to generate pluripotent cells from differentiated cells. However, they are poorly efficient and other unknown factors might be required to increa...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-31691 | biostudies-arrayexpress
UnknownRevealing the Genetic Components Responsible for the Unique Photosynthetic Stem Capability of the Wild Almond Prunus arabica (Olivier) Meikle.
Not available
S-EPMC8657148 | biostudies-literature
TranscriptomicsA novel class of alternative 3M-bM-^@M-^Y-terminal exons is involved in cell-cycle regulation by topoisomerase inhibitors
Alternative 3M-bM-^@M-^Y-terminal exons, which use intronic polyadenylation sites, are generally unconserved and lowly expressed, while the main gene products end in the last exon of genes. In this study, we discover a class of human genes, where the last exon appeared recently during evolution, and...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-53474 | biostudies-arrayexpress
UnknownScreening of tropical isolates of Metarhizium anisopliae for virulence to the red palm weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae).
Not available
S-EPMC4947082 | biostudies-literature
MetabolomicsInsights into the stereochemical mechanism of the B12-dependent radical SAM glutamine C- methyltransferases QCMT
Methyl-coenzyme M reductase (MCR) is a crucial enzyme for methanogenesis and harbors several unusual post-translational modifications. Recent studies have identified glutamine C-methyltransferase (QCMT), as a B12-dependent radical SAM enzyme responsible for methylating a glutamine residue within the...
2026-04-28 | MTBLS14287 | MetaboLights
UnknownFeasibility and acceptability of mindful recovery opioid use care continuum (M-ROCC): A concurrent mixed methods study.
Not available
S-EPMC8478704 | biostudies-literature
Transcriptomicsexpression profiling data of CLB-GA neuroblastoma cells upon TAE-684, Crizotinib, X-396, LDK378, Trametinib, BEZ-235 and Vandetanib
Treatment of the CLB-GA cell line with complementary ALK, MEK, PI3K/mTOR or RET inhibitors (and DMSO (VWR) as control) was performed in duplicate for each drug using the GI50 concentrations (see further): 0.5M-k_M Crizotinib (Pfizer/Sigma-Aldrich); 0.06M-k_M X-396 (VWR); 0.2M-k_M LDK378 (Hoelzel Bio...
ORGANISM(S): homo sapiens 
2015-05-04 | E-MTAB-3206 | biostudies-arrayexpress
ProteomicsTEAD inhibitor K-975 enhances KRASG12C inhibitor adagrasib-mediated cancer cell proliferation inhibition via dual cell cycle arrest
Here we investigate the effect of the dual inhibition, in KRASG12C mutated NSCLC cells, using the KRASG12Ci adagrasib (MRTX849) and the pan-TEAD inhibitor (TEADi) K-975. We show that K-975 enhances adagrasib-induced tumor cell growth inhibition in cancer cells. Mechanistically, we detect a downregul...
ORGANISM(S): Homo Sapiens (human) 
2023-05-12 | PXD039726 | JPOST Repository
UnknownTranscriptome analysis of Phoenix canariensis Chabaud in response to Rhynchophorus ferrugineus Olivier attacks.
Not available
S-EPMC4604324 | biostudies-literature
TranscriptomicsmRNA expression profiles of SK-N-AS neuroblastoma cells with induced ALK-wt, ALK-F1174L or ALK-R1275Q
Establishment of inducible SK-N-AS ALKwt, ALKF1174L and ALKR1275Q cell lines Human neuroblastoma SK-N-AS cells were electroporated with pcDNA6/TR (Invitrogen) using the NeonM-eM-( Transfection System (Life Techologies). Single cell clones were generated using blasticidin (7.5M-eM-5g/ml) and limited ...
ORGANISM(S): homo sapiens 
2015-05-04 | E-MTAB-3207 | biostudies-arrayexpress
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