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TranscriptomicsExpression quantitative trait loci (eQTL) analysis of Brassica rapa under varying soil phosphorus (P) supplies
The aim of this study was to identify eQTL in Brassica rapa grown under altered soil phosphorus (P) supply, to understand better the genetic architecture of P-use efficiency (PUE) in plants. Recombinant inbred lines (RILs) of the BraIRRI mapping population were grown at adequate and growth-limiting ...
ORGANISM(S): Brassica rapa 
2011-06-29 | E-GEOD-27052 | biostudies-arrayexpress
MetabolomicsMulti-omics characterization of acquired Olaparib resistance in BRCA1 and BRCA2 mutant breast cancer cell lines
Poly (ADP-ribose) polymerase inhibitors (PARPi) are widely used as targeted therapies against breast cancers with BRCA mutations. However, the development of resistance to PARPi poses a significant challenge for long-term efficacy of these therapies, warranting further understanding of mechanisms of...
2026-05-11 | MTBLS12109 | MetaboLights
TranscriptomicsCanary Ovarian Cell Line Gene Expression
All cell lines were cultured according to the specifications outlined by ATCC. Cell lines were grown to 80% confluence, then serum-deprived in 0.5% FBS for 24 hours before harvesting. Cells were washed twice with Hank's Balanced Salt Solution (Invitrogen, Carlsbad, California) and drained. 1 mL of S...
ORGANISM(S): Homo sapiens 
2011-02-12 | E-GEOD-27225 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon cancer cell line SW620 treated with docosahexaenoic acid
The human colon cancer cell line SW620 was supplemented with DHA (70 µM) or an equal volume of ethanol (control). Total RNA was isolated after 6 h and used for Affymetrix gene expression profiling.
ORGANISM(S): Homo sapiens 
2009-06-01 | E-MEXP-2010 | biostudies-arrayexpress
TranscriptomicsRegional brain expression maps for microRNAs in rats
MicroRNA transcriptional profiling of male Sprague-Dawley rats rat brains comparing microRNA abundance in five different brain regions. Two-condition experiment, regional brain samples vs. universal brain reference. Biological replicates: 4 samples from each region. One sample per array. Each array ...
ORGANISM(S): Rattus norvegicus 
2009-11-16 | E-GEOD-16725 | biostudies-arrayexpress
ProteomicsThe Human Cell Line Phosphoproteome Atlas: A Deep Empirical Resource Revealing Kinase Activity Landscapes
Protein phosphorylation orchestrates cellular signaling and controls diverse biological processes, with dysregulation driving disease, notably cancer. Comprehensive, high-throughput phosphoproteomics remains limited by detection sensitivity, data completeness, and computational bottlenecks, especial...
ORGANISM(S): Homo sapiens (Human) 
2026-08-03 | PXD068583 | Pride
ProteomicsSystematic evaluation and modulation of HLA class I downregulation in Merkel cell carcinoma
Lee PC, Klaeger S, Le PM, Korthauer K, Cheng J, Wong A, Tarren A, Lemvigh C, Sarkizova S, Li L, Frost TC, Nomburg J, Liu X, Pomerance L, Doherty L, Witten E, Zhang W, Apffel A, Wallace L, Neuberg D, Olsen L, Thakuria M, Clauser K, Starrett G, Doench J, Buhrlage SJ, Carr SA, DeCaprio JA, Wu CJ, Keski...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-20 | MSV000087251 | MassIVE
Proteomics,MultiomicsmiR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signaling in human colorectal adenocarcinoma cells
Oxaliplatin (oxPt) resistance in colorectal cancers (CRC) is a major unsolved problem. Consequently, predictive markers and a better understanding of resistance mechanisms are urgently needed. To investigate if the recently identified predictive miR-625-3p is functionally involved in oxPt resistance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080762 | MassIVE
UnknownIdentifying drivers of first-line HR+/HER2- metastatic breast cancer treatment choices.
Not available
S-EPMC11508941 | biostudies-literature
ProteomicsProteomics of NGF-TrkA signaling dynamics in neuroblastoma cells
We used quantitative mass spectrometry-based proteomics to unravel global nerve growth factor (NGF)-induced TrkA signaling dynamics at the interactome, phosphoproteome and proteome level. A tetracycline-inducible system for TrkA expression was generated in the human neuroblastoma cell line, SH-SY5Y....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080834 | MassIVE
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