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GenomicsDistinct Gene Regulatory Pathways for Human Innate Versus Adaptive Lymphoid Cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-05-13 | E-GEOD-78897 | biostudies-arrayexpress
TranscriptomicsTargeted chromatin profiling reveals novel enhancers in Ig heavy and light chain loci.
Chip-chip from pro-B cells from Rag1KO mice for H3K27ac and RNA Pol II Identification of novel enhancers from Ig heavy and light chain loci Rag1KO pro-B epigenetic landscape at Ig heavy and light chain loci
ORGANISM(S): Mus musculus 
2014-01-03 | E-GEOD-53766 | biostudies-arrayexpress
TranscriptomicsTissue-specific changes in Tcrb conformation
We report the changes in Tcrb interactome upon transitioning from DN to DP stage of thymocyte development Examination of the interactomes of Eb and Trbv5 viewpoints in RAG-deficient DN and DP thymocytes
ORGANISM(S): Mus musculus 
2015-07-08 | E-GEOD-68955 | biostudies-arrayexpress
GenomicsDistinct Gene Regulatory Pathways for Human Innate Versus Adaptive Lymphoid Cells [ChIP-seq & ATAC-seq]
Innate lymphoid cells (ILCs) serve as sentinels in mucosal tissues, sensing release of soluble inflammatory mediators, rapidly communicating danger via cytokine secretion, and functioning as guardians of tissue homeostasis. Although ILCs have been studied extensively in model organisms, little is kn...
ORGANISM(S): Homo sapiens 
2016-05-13 | E-GEOD-77299 | biostudies-arrayexpress
GenomicsMicrobial-Derived Metabolites Regulate the Colonic Crypt Niche
In the mammalian intestine, crypts of Leiberkühn house intestinal epithelial stem /progenitor cells at their base. We found that the presence of this structure was supported by the physiologic role of a prominent bacterial metabolite, butyrate. This bacterially-produced short chain fatty acid inhib...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-74601 | biostudies-arrayexpress
TranscriptomicsDistinct Gene Regulatory Pathways for Human Innate Versus Adaptive Lymphoid Cells [gene expression]
Innate lymphoid cells (ILCs) serve as sentinels in mucosal tissues, sensing release of soluble inflammatory mediators, rapidly communicating danger via cytokine secretion, and functioning as guardians of tissue homeostasis. Although ILCs have been studied extensively in model organisms, little is kn...
ORGANISM(S): Homo sapiens 
2016-05-13 | E-GEOD-78896 | biostudies-arrayexpress
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