The integration of omics technologies into molecular biological research has transformed it into a field where a system can be investigated as a whole by combining information from multiple biochemical layers. This extension of traditional molecular biology, where various data sources are conside...

Abstract This study focused on elucidating the lignocellulose degradation mechanism of Pholiota adiposa strain YAHS, aiming to provide theoretical basis and microbial resources for straw biorefining. Using the aniline blue-guaiacol plate screening method, 11 fungal strains were isolated from the ...

As the petrochemical industry continues to advance, the exacerbation of ecological imbalance and environmental degradation due to petroleum pollution is increasingly pronounced. The synergistic interaction between plants and microorganisms are pivotal in the degradation of petroleum hydrocarbons;...

Huaganjian (HGJ) is a traditional Chinese medicinal formula with liver-protective effects. However, the pharmacological mechanisms of the effects of HGJ on cholestatic liver fibrosis (CLF) are yet to be clarified. To evaluate the effects of HGJ on CLF and elucidate the underlying mechanisms, C57B...

Here, we selected Roseovarius nubinhibens as the model organism to comprehensively interrogate aromatic compound metabolism in marine Roseobacter clade. First, we preliminarily elucidated the three distinct mechanisms of aromatic compound transmembrane transport in R. nubinhibens. By integrating ...

Alcohol-related brain damage (ARBD) constitutes a major global public health issue and is often comorbid with neuropsychiatric disorders such as Alzheimer's and Parkinson's diseases. Ferroptosis, a form of regulated cell death characterized by iron dependency and lipid peroxidation, has been impl...

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis.

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

Background: Antler is an important economic trait of sika deer (Cervus nippon), capable of rapid growth without signs of tumorigenesis. However, the molecular mechanisms underlying its unique growth pattern remain poorly understood. This study conducted a combined transc...