Oncogenesis - OmicsDI

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Organisms

Homo sapiens (547)
Mus musculus (173)
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human gammaherpesvirus 4 (1)
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human vaginal metagenome (1)
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Repository

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Tissue

Cell culture (28)
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Breast Normal (1)
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Post-stasis (1)
Mild hyperglycemia (1)
Undifferentiated sarcoma (1)
Pre-tumoral lesion in a mouse model of human adamantinomatous craniopharyngioma (ACP) (1)
Precursor T lymphoblastic leukemia (1)
Mild hyperglycemia, liver dysfunction, and renal glycosuria (1)
MPIN (murine prostatic intraepithelial neoplasia) (1)
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Hepatoblastoma (1)
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Technology Type

Mass Spectrometry (62)
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Affinity purification coupled with mass spectrometry proteomics (7)
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Gel-based experiment (5)
Illumina HiSeq 2500 (3)
Data-independent acquisition (3)
ILLUMINA, Illumina HiSeq 2500 (2)
Illumina HiSeq 2000, ILLUMINA (2)
SRM/MRM (2)
Humanomniexpress-24-v1-1-a, Illumina HiSeq 2000, HiSeq X Ten, Illumina HiSeq 2500, Illumina HiSeq 4000, ILLUMINA (1)
Illumina HumanOmni5 (1)
HiSeq X Ten, Illumina HiSeq 2000, Illumina MiSeq, ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiScanSQ, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500, HiSeq X Ten (1)
Illumina HiSeq 2500, ILLUMINA (1)
NextSeq 500, Illumina HiSeq 2000, ILLUMINA (1)
Illumina_450K (1)
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454 GS FLX Titanium, Illumina HiSeq 2000 (1)
Illumina Genome Analyzer, Illumina HiSeq 2000, Illumina MiSeq, Affymetrix_U133plus2- (1)
Illumina Genome Analyzer IIx, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, Illumina Genome Analyzer IIx (1)
AB SOLiD System 3.0 (1)
Illumina HiSeq 2000, Illumina_2.5M (1)
NMR spectroscopy (1)

Instrument Platform

Illumina NovaSeq 6000 (20)
Illumina HiSeq 2500 (19)
NextSeq 500 (15)
Illumina HiSeq 2000 (9)
Illumina HiSeq 4000 (5)
Scanning hardware (4)
ScanArray 4000XL [PerkinElmer] (3)
Illumina MiSeq (3)
Illumina HiSeq 1500 (3)
Illumina HiScanSQ (2)
Illumina NovaSeq X (2)
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GeneChip® Pico Kit (Affymetrix) (1)
Affymetrix Clariom™ S (400 Format) (1)
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RNeasy 96-well plate kit (1)
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10X (1)
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Miltenyi Biotec (cat no. 130-096-730) ,Fortessa X-20 flow cytometer (BD Biosciences) (1)
Zephyr G3 NGS workstation (1)
MiRNeasy Micro kit (1)
Radial JawTM (1)
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Affymetrix Mouse Gene 1.0 ST (1)

Publication Date

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2007 (58)
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2019 (39)
2005 (26)
2006 (10)
2004 (4)
2003 (3)
2002 (2)

UNIPROT ID/AC

P26233 (1)
Q91757 (1)
P70039 (1)
Q9YGY0 (1)
P51142 (1)
P60953 (1)
P24394 (1)
P51452 (1)
P01116 (1)
P01133 (1)
P00533 (1)
P29353 (1)
P04049 (1)
Q02750 (1)
P28482 (1)
Q07889 (1)
P20936 (1)
P62993 (1)
A0A024R563 (1)
A0A024R8H9 (1)
A0A024RAN2 (1)
A0A024RC46 (1)
A0A075B6P5 (1)
A0A087WTX5 (1)
A0A087WVW2 (1)
A0A087WVZ5 (1)
A0A087WXI0 (1)
A0A087WYL9 (1)
A0A087WZE9 (1)
A0A087X130 (1)

ENSEMBL ID

ENSG00000147251 (1)
ENSG00000170477 (1)

CHEBI ID

CHEBI:30769 (6)
CHEBI:16027 (6)
CHEBI:15721 (4)
CHEBI:15422 (4)
CHEBI:16761 (4)
CHEBI:16908 (4)
CHEBI:18117 (1)
CHEBI:16464 (1)
CHEBI:40595 (1)
CHEBI:13389 (1)
CHEBI:58273 (1)
CHEBI:17050 (1)
CHEBI:58121 (1)
CHEBI:57737 (1)
CHEBI:57642 (1)
CHEBI:26689 (1)
CHEBI:30956 (1)
CHEBI:25523 (1)
CHEBI:16077 (1)
CHEBI:28087 (1)
CHEBI:24996 (1)
CHEBI:18367 (1)
CHEBI:48153 (1)
CHEBI:16938 (1)
CHEBI:17138 (1)
CHEBI:15361 (1)
CHEBI:17665 (1)
CHEBI:16526 (1)
CHEBI:18021 (1)
CHEBI:15946 (1)

Metabolite Name

Creatinine (9)
Hypoxanthine (8)
Adenosine (7)
Creatine (7)
Indole-3-carbinol (5)
Stearoylcarnitine (5)
PC(16:0/16:0) (5)
Betaine aldehyde (5)
Thiamine (5)
Niacinamide (5)
L-Histidine (5)
Choline (5)
N-Acetylputrescine (5)
Guanine (5)
Cytosine (5)
L-Carnitine (5)
N6,N6,N6-Trimethyl-L-lysine (4)
SM(d18:1/24:1(15Z)) (4)
Uracil (4)
Betaine (4)
Propionylcarnitine (4)
Phytolaccasaponin G (4)
Lidocaine (4)
Diethanolamine (4)
Triethanolamine (4)
Piperidine (4)
L-Threonine (4)
Biliverdin (4)
Pyridoxamine (4)
L-Glutamic acid (4)

First Public Date

2014 (162)
2025 (96)
2022 (91)
2026 (82)
2023 (81)
2024 (74)
2021 (65)
2020 (55)
2019 (52)
2018 (47)
2017 (38)
2015 (29)
2013 (25)
2016 (18)

Modelling Approach

Ordinary differential equation model (4)

Study status

Completed (1)

Lab affiliation

1: Evotec (München) GmbH, Am Klopferspitz 19a, 82151 Martinsried, Germany 2: Cell Signaling Group, Department of Molecular Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany (1)
1Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada 2Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada Departments of Biochemistry and Biology, Boston University, 71 E. Concord St, Boston, MA 02118, USA (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA 3Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 3Biological and Biomedical Sciences Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. (1)
Additional Professor, Department of Medical Oncology (Lab.), Dr B.R.A.I.R.C.H., AIIMS, New Delhi (1)
Assistant Professor, Dept of Obstetrics & Gynaecology, Faculty of Medicine, The Ubiversity of Hong Kong (1)
Biological Sciences, University of Southampton (1)
CRUK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK. (1)
Center for Network Systems Biology, Boston University, USA (1)
Centre de recherche hopital Maisonneuve Rosemont (1)
Centre for Genomics and Computational Biology. Barts Cancer Institute / Queen Mary University of London (1)
Chair of Proteomics and Bioanalytics, Technische Universität München, Germany (1)
Chemistry Department, The Scripps Research Institute, La Jolla, California, USA (1)
Cleveland Clinic Florida Research and Innovation Center (1)
Clinical and Experimental Sciences Unit, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK Centre for Proteomic Research, Institute for Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK (1)
Department of Cell Biology, Microbiology, and Molecular Biology University of South Florida Tampa, FL, USA 33620 (1)
Department of Chemistry, National Cheng Kung University, Taiwan (1)
Department of Chemistry, UC Riverside (1)
Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy (1)
Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden. (1)
Department of pharmaceutical chemistry, school of pharmacy, University of California San Francisco (1)
Director of Proteomics Core (1)
Director of the Proteomics Core at Indiana University School of Medicine (1)
Division of Hematology, Department of Medicine, Stanford University School of Medicine Department of Chemistry, Northwestern University (1)
Dr. Robert Ahrends Group leader lipidomics Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Otto-Hahn-Straße 6b 44227 Dortmund, Germany (1)
Epigenetics and Cell Fate Centre CNRS UMR7216 – Université Paris Cité Lamarck B building, 4th floor, room 413 35, rue Hélène Brion 75205 Paris Cedex 13 +33157278981 (1)
Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland (1)
Functional Proteome Analysis, German Cancer Research Center(DKFZ) (1)
Functional Proteomics Laboratory Department of Science and Technology, Federal University of São Paulo (ICT-UNIFESP), São José dos Campos, SP, Brazil, Rua Talim, 330, 12231-280, Tel.: +55 11 3385-4135 ext. 9727. (1)
Functional Proteomics Laboratory, Department of Science and Technology, Federal University of Sao Paulo, UNIFESP, Sao Jose dos Campos, Sao Paulo, Brazil (1)

Keyword

Inflammatory bowel disease (1)

IsPrivate

False (4)

Classification

viruses (2)
bacteria (1)

Modification

-17.026549 (1)
-18.010565 (1)
15.994915 (1)
42.010565 (1)
4x(2)H labeled dimethylated residue (1)
57.021464 (1)

Study type

Transcription profiling by array (1129)
RNA-seq of coding RNA (123)
Comparative genomic hybridization by array (92)
Methylation profiling by array (77)
ChIP-seq (64)
Unknown experiment type (26)
RNA-seq of non coding RNA (23)
Methylation profiling by high throughput sequencing (22)
Genotyping by array (21)
ChIP-chip by tiling array (16)
MicroRNA profiling by array (14)
ChIP-chip by array (12)
DNA-seq (12)
Transcription profiling by RT-PCR (11)
RNA-seq of coding RNA from single cells (11)
Other (10)
RNAi profiling by array (5)
Transcription profiling by SAGE (4)
Proteomic profiling by array (4)
Cell line - One-color microarray (3)
Cell line - High-throughput sequencing (3)
RNA-seq of total RNA (3)
MicroRNA profiling by high-throughput sequencing (2)
Human - High-throughput sequencing (2)
Whole chromosome random sequencing (2)
Transcription profiling by high throughput sequencing (1)
Cell line - Two-color microarray (1)
Human - Two-color microarray (1)
MeDIP-seq (1)
Translation profiling (1)

Release Date

2021 (470)
2022 (466)
2023 (435)
2015 (428)
2014 (421)
2020 (407)
2016 (405)
2025 (374)
2013 (355)
2018 (333)
2012 (331)
2019 (321)
2017 (304)
2024 (288)
2010 (279)
2011 (273)
2009 (156)
2008 (156)
2007 (90)
2026 (63)
2005 (37)
2006 (28)
2004 (23)
2003 (19)
2001 (8)
2002 (6)
1998 (5)
2000 (3)
1997 (3)
1999 (2)

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O-GlcNAcylation Promotes Cerebellum Development and Medulloblastoma Oncogenesis via SHH Signaling

Sonic hedgehog (Shh) signaling plays a critical role in regulating cerebellum development by maintaining the physiological proliferation of granule neuron precursors (GNPs), and its dysregulation leads to the oncogenesis of medulloblastoma. O-GlcNAcylation (O-GlcNAc) of proteins is an emerging regul...

ORGANISM(S): Homo Sapiens

2022-06-02 | PXD034270 |

FOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression.

Not available

S-EPMC4767937 | biostudies-literature

Viral integration transforms chromatin to drive oncogenesis

PRJNA598867 | ENA

Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects.

Not available

S-EPMC3417111 | biostudies-literature

Mediator Subunit 30 Directs Myc Oncogenesis [Cut&Tag]

PRJNA899522 | ENA