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The paper describes a model of oncolytic virotherapy. Created by COPASI 4.25 (Build 207) This model is described in the article: A mathematical model verifying potent oncolytic efficacy of M1 virus Zizi Wang, Zhiming Guo, Huaqin Peng Mathematical Biosciences 276 (2016) 19–27 Abstract: Motivat...
2024-09-02 | BIOMD0000000780 | BioModels
The paper describes a basic model of oncolytic virotherapy. Created by COPASI 4.25 (Build 207) This model is described in the article: A mathematical model verifying potent oncolytic efficacy of M1 virus Zizi Wang, Zhiming Guo, Huaqin Peng Mathematical Biosciences 276 (2016) 19–27 Abstract: M...
2024-09-02 | BIOMD0000000782 | BioModels
The paper describes a model of oncolytic virotherapy. Created by COPASI 4.25 (Build 207) This model is described in the article: A mathematical model verifying potent oncolytic efficacy of M1 virus Zizi Wang, Zhiming Guo, Huaqin Peng Mathematical Biosciences 276 (2016) 19–27 Abstract: Motivat...
2024-09-02 | BIOMD0000000781 | BioModels
This mathematical model of the role of the innate immune responses generated by macrophages in the context of anti-tumour oncolytic viral therapies is described in the publication: Nada Almuallem, Dumitru Trucu, Raluca Eftimie. "Oncolytic viral therapies and the delicate balance between virus-macrop...
2024-09-02 | BIOMD0000001033 | BioModels
Expression data from colorectal carcinoma HCT-15 treated with oncolytic virus M1 and U0126
Mass spectrometry raw data for submitting manuscript entitled "Directed natural evolution generates a next-generation oncolytic virus with a high potency and safety profile for multiple solid tumors" to Nature Communications.
ORGANISM(S): Homo sapiens (Human) 
2023-05-22 | PXD037429 | Pride
Virus infection is a kind of immune stimulation, except anti-viral factors, virus also induce tumor cells to secret cytokines which act on neighboring cells. Figuring out the exact cytokines upregulated by M1 virus is of great significance. We used microarry data to detail the expression of cytokine...
ORGANISM(S): Homo sapiens 
2016-12-27 | GSE92918 | GEO
Virus infection is a kind of immune stimulation, we previously found that inhibition of Ras signaling by U0126 supress the infection of M1 virus, thus we predicted that U0126 might increase the antiviral effect, ultimately inhibit the replication of M1 virus. We plan to figure it out from the expres...
ORGANISM(S): Homo sapiens 
2019-07-19 | GSE134487 | GEO
Oncolytic virus M1 functions as a bi-functional checkpoint inhibitor to enhance the antitumor activity of DC vaccine
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