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ProteomicsDynamic Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery Requires Iron-Sulfur Cluster Incorporation of CIAO3
Cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. This delivery process is regulated by availability of iron and oxygen, but it remains unclear how CIA components orchestrate the cluster...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-16 | MSV000088394 | MassIVE
ProteomicsFIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1.
The asparagine hydroxylase, factor inhibiting HIF (FIH) confers oxygen-dependence upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hypoxia. Studies investigating whether asparagine hydroxylation is a general regulatory oxygen-dependent modification hav...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080695 | MassIVE
UnknownHighly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1.
Not available
S-EPMC6151090 | biostudies-literature
ProteomicsIron-Regulated Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery
The cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. Although the delivery process is regulated by the availability of iron and oxygen, it remains unclear how CIA components orchestrate...
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD033557 | panorama
Unknown"The project did not come to us with a solution": Perspectives of research teams on implementing a study about electronic health record-embedded individualized pain plans for emergency department treatment of vaso-occlusive episodes in adults with sickle cell disease.
Not available
S-EPMC10641983 | biostudies-literature
MetabolomicsABHD11/ROLIP maintains the TCA cycle by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex
2-oxoglutarate (2-OG) relates mitochondrial metabolism to cell function: conversion of 2-OG to succinyl-CoA by the 2-OG dehydrogenase complex (OGDHc) is rate-limiting for the Tricarboxylic Acid (TCA) cycle, but 2-OG is also required for oxygen sensitive enzymes (2-OG dependent dioxygenases) that hav...
2020-08-10 | MTBLS1875 | MetaboLights
ProteomicsTime-resolved Proteome and Metabolome Profiling of Normal Lung Development
Proteomics data from mouse lung; performing unbiased protein and metabolite profiling for normal lung development
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-06-22 | MSV000081190 | MassIVE
UnknownStomach cancer elective surgery morbidity and mortality at 90-Day (Hold Study): a prospective, international collaborative cohort study.
Not available
S-EPMC12618408 | biostudies-literature
UnknownA global metagenomic map of urban microbiomes and antimicrobial resistance.
Not available
S-EPMC8238498 | biostudies-literature
UnknownQuantifying health facility service readiness for small and sick newborn care: comparing standards-based and WHO level-2 + scoring for 64 hospitals implementing with NEST360 in Kenya, Malawi, Nigeria, and Tanzania.
Not available
S-EPMC10935770 | biostudies-literature
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