Oocyte maturation.

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Tissue

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Instrument Platform

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2012 (26)
2011 (26)
2013 (25)
2015 (24)
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2018 (21)
2017 (21)
2008 (13)
2009 (10)
2007 (8)
2006 (5)

UNIPROT ID/AC

P12965 (1)
Q90W58 (1)
Q05116 (1)
P26696 (1)
A0A1L8EJM5_XENLA (1)
A0A1L8EJN0_XENLA (1)
A0A1L8EJN9_XENLA (1)
A0A1L8EJS5_XENLA (1)
A0A1L8EJX0_XENLA (1)
A0A1L8EJY7_XENLA (1)
A0A1L8EK25_XENLA (1)
A0A1L8EKP4_XENLA (1)
A0A1L8EKW3_XENLA (1)
A0A1L8EL06_XENLA (1)
A0A1L8ELD8_XENLA (1)
A0A1L8ELX8_XENLA (1)
A0A1L8EM01_XENLA (1)
A0A1L8EM21_XENLA (1)
A0A1L8EM44_XENLA (1)
A0A1L8EMI9_XENLA (1)
A0A1L8EMP4_XENLA (1)
A0A1L8EMU2_XENLA (1)
A0A1L8EMY4_XENLA (1)
A0A1L8EMY5_XENLA (1)
A0A1L8EMZ6_XENLA (1)
A0A1L8EN29_XENLA (1)
A0A1L8EN71_XENLA (1)
A0A1L8ENA1_XENLA (1)
A0A1L8ENF2_XENLA (1)
A0A1L8ENH3_XENLA (1)

CHEBI ID

CHEBI:175859 (1)
CHEBI:89105 (1)
CHEBI:186609 (1)
CHEBI:174625 (1)
CHEBI:187055 (1)
CHEBI:174976 (1)
CHEBI:175677 (1)
CHEBI:190179 (1)
CHEBI:89594 (1)
CHEBI:89533 (1)
CHEBI:192340 (1)
CHEBI:192033 (1)
CHEBI:176221 (1)
CHEBI:49007 (1)
CHEBI:179431 (1)
CHEBI:174191 (1)
CHEBI:67591 (1)
CHEBI:174376 (1)
CHEBI:84495 (1)
CHEBI:84816 (1)
CHEBI:44395 (1)
CHEBI:3689 (1)
CHEBI:38728 (1)
CHEBI:184296 (1)
CHEBI:169036 (1)
CHEBI:184138 (1)
CHEBI:174681 (1)
CHEBI:173801 (1)
CHEBI:190405 (1)
CHEBI:185178 (1)

Metabolite Name

L-Proline (3)
L-Arginine (3)
Choline (3)
Phosphorylcholine (3)
L-Glutamine (3)
Creatinine (3)
L-Methionine (3)
L-Phenylalanine (3)
Phenylacetaldehyde (2)
Stigmasterol (2)
L-Norleucine (2)
Leucine (2)
PC(16:0/16:0) (2)
Picolinic acid (2)
Betaine (2)
Propionylcarnitine (2)
Thiamine (2)
Sphingosine (2)
Nicotinamide ribotide (2)
Niacinamide (2)
L-Lysine (2)
Diethanolamine (2)
Acetylcysteine (2)
7-Dehydrodesmosterol (2)
5'-Methylthioadenosine (2)
Aspartame (2)
Triethanolamine (2)
Cholesterol (2)
L-Kynurenine (2)
L-Histidine (2)

IsPrivate

False (1)

First Public Date

2026 (68)
2025 (67)
2024 (52)
2014 (50)
2023 (43)
2019 (32)
2021 (31)
2022 (27)
2020 (20)
2017 (18)
2018 (16)
2016 (13)
2015 (11)
2013 (5)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (112)
RNA-seq of coding RNA (25)
ChIP-chip by tiling array (9)
Other (5)
RNA-seq of non coding RNA (5)
Unknown experiment type (3)
Transcription profiling by SAGE (2)
Methylation profiling by array (2)
RNA-seq of coding RNA from single cells (2)
Methylation profiling by high throughput sequencing (2)
RNAi profiling by array (1)
ChIP-chip by array (1)
Bisulfite-seq (1)
RIP-seq (1)

Release Date

2021 (191)
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2016 (99)
2014 (85)
2015 (83)
2013 (65)
2011 (51)
2010 (50)
2012 (38)
2009 (28)
2026 (27)
2008 (25)
2007 (15)
2006 (14)
2005 (7)
2004 (7)
2003 (7)
2002 (6)
1999 (4)
2001 (2)
2000 (2)
1998 (2)
1996 (1)

Lab affiliation

Clinical Chemistry, Department of Translational Medicine, Lund University, Skane University Hospital Malmö, 205 02 Malmö, Sweden. (2)
Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain (2)
State Key Laboratory of Reproductive Medicine, Nanjing Medical University (2)
CEA-Marcoule Institute of Environnemental Biology and Biotechnology Department of Biochemistry and Nuclear Toxicology Biochemistry of Perturbed Systems Laboratory France (1)
Center for Reproductive Medicine, Shandong University (1)
Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China (1)
Center of Reproductive Medicine, Huai’an Maternity and Child Health Care Hospital, Huai’an, 223002, P.R. China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, 210029, P.R. China (1)
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. (1)
Clinic of Reproductive Medicine, Department of Farm Animals Vetsuisse-Faculty University Zurich (1)
Clinic of Reproductive Medicine, Vetsuisse Faculty, University of Zurich (1)
College of Animal Science, Shanxi Agricultural University (1)
Department of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, the Hebrew University, Rehovot 76100, Israel Center of Excellence in Agriculture and Environmental Health, the Hebrew University, Rehovot 76100, Israel (1)
Department of Biology, AG Stengel, University of Konstanz, Germany (1)
Department of Biology, Cellular Proteostasis and Mass Sepectrometry, University of Konstanz (1)
Department of Biology, Syracuse University, Syracuse, NY, USA (1)
Department of Biomolecular Medicine, Ghent University, Ghent, Belgium VIB Center for Medical Biotechnology, VIB, Ghent, Belgium (1)
Department of Cell Biology and Histology, Faculty of Medicine, Campus Mare Nostrum,University of Murcia, 30100 Murcia, IMIB, Spain (1)
Department of Comparative Biosciences, University of Illinois at Urbana-Champaign (1)
Department of Genetics, Cell Biology, and Development, University of Minnesota, 4-208 MCB, 420 Washington Avenue SE, Minneapolis, MN 55455. Tel: 612-624-3955; FAX: 612-626-6140. (1)
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada;Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada;Department of Clinical Biochemistry, University Health Network, Toronto, Canada (1)
Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences; Göttingen, Germany (1)
Department of Molecular Endocrinology, National Institute for Research in Reproductive Health, Indian Council of Medical Research, Mumbai 400012, India (1)
Department of Neurobiology and Developmental Science, University of Arkansas for Medical Sciences, Little Rock, AR (1)
Department of Translational Medicine, Lund University (1)
Department of Zoology and Anthropology, Faculty of Natural Sciences and Informatics, Constantine the Philosopher University in Nitra (1)
Deputy head of department at Department of Translational Medicine. Lund University. Principal investigator at CEBMMS PI. Professor at Clinical Chemistry, Malmö Professor at Clinical Protein Science and Imaging Professor at Department of Clinical Sciences, Lund (1)
EMBL Heidelberg (1)
ETH Zürich, Department of Environmental Systems Science (1)
Environmental Biochemistry Laboratory, Institute of Biology of the Karelian Research Centre of the Russian Academy of Sciences, Petrozavodsk, Russia (lab head) (1)
Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, United Kingdom (1)

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Comprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation

In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...

2025-08-27 | MTBLS12325 | MetaboLights

Uridine restores oocyte quality and mitigates female reproductive aging by inhibition of ferroptosis in mice

Advanced maternal age is a key factor in female infertility, primarily due to declines in ovarian reserve and oocyte quality. However, the metabolic mechanisms underlying reproductive aging are still poorly understood. Here, we show that uridine levels in the plasma and ovaries of aged mice are s...

2026-03-03 | MTBLS13957 | MetaboLights

Transcription profiling of immature germinal vesicle stage oocytes with mature metaphase II oocytes to identify and characterize the changed and stable transcripts during mouse oocyte maturation.

There is massive destruction of transcripts during maturation of mouse oocytes. The objective of this project was to identify and characterize the transcripts that are degraded versus those that are stable during the transcriptionally silent germinal vesicle (GV)-stage to metaphase II (MII)-stage t...

ORGANISM(S): Mus musculus

2007-11-13 | E-GEOD-5668 | biostudies-arrayexpress

Effects of in vitro maturation on oocyte gene expression

In vitro oocyte maturation (IVM) holds great promise as a tool for enhancing clinical treatment of infertility, enhancing availability of non human primates for development of disease models, and facilitating endangered species preservation. However, IVM outcomes have remained significantly below s...

ORGANISM(S): Macaca mulatta

2009-05-20 | E-GEOD-11895 | biostudies-arrayexpress

SAGE in Cultured Murine COC During Early Maturation

In cultured cumulus oocyte complexes (COC) FSH induces gene transcription required for germinal vesicle breakdown (GVBD). Experiments were performed to determine the critical period when gene transcription is required for GVBD and identify candidate mRNAs involved. Experiment I: murine COC were cult...

ORGANISM(S): Mus musculus

2006-08-31 | E-GEOD-5568 | biostudies-arrayexpress

Single-cell quantitative proteomic analysis of oocyte maturation revealed high heterogeneities in human in vitro matured oocytes

In this study we investigated the protein expression patterns during human oocyte in vitro and in vivo maturation (IVO) by single-cell quantitative proteomic analysis of 36 human oocytes. Among 2,094 proteins quantified in 34 oocytes (GV: 11 oocytes, IVM: 12 oocytes, IVO: 11 oocytes), 224 were diffe...

ORGANISM(S): Homo sapiens (Human)

2022-08-02 | PXD023366 | Pride

Human oocyte maturation Single cell proteomics

Comparison of the human oocyte to its sister polar body

Clinicians need additional metrics for predicting quality of human oocytes for IVF procedures. Human polar bodies reflect the oocyte transcript profile. Quantitation of polar body mRNAs could allow for both oocyte ranking and embryo preferences in IVF applications. The transcriptome of a polar body ...

ORGANISM(S): Homo sapiens

2011-10-12 | E-GEOD-32689 | biostudies-arrayexpress

Effects of Dcp1a and Dcp2 knockdown during mouse oocyte maturation

Oocyte maturation is accompanied by a transition from mRNA stability to instability. We investigated the role of DCP1A and DCP2, proteins responsible for mRNA decapping, in mRNA destabilization during mouse oocyte maturation. siRNA-mediated knockdown of both Dcp1a and Dcp2 transcripts prior to ini...

ORGANISM(S): Mus musculus

2013-02-06 | E-GEOD-27049 | biostudies-arrayexpress

Transciption profiling of human endometrial biopsies taken on the day of oocyte retrieval in stimulated IVF cycles with 1 or 2 embryos replaced on day 3 in the same cycle

In GnRH-antagonist/rec-FSH stimulated cycles, advanced endometrial maturation on the day of oocyte retrieval correlates with altered gene expression Experiment Overall Design: Endometrial biopsies taken on the day of oocyte retrieval in stimulated IVF cycles with 1 or 2 embryos replaced on day 3 in ...

ORGANISM(S): Homo sapiens

2009-11-16 | E-GEOD-13027 | biostudies-arrayexpress

Polysome-bound mRNA during oocyte maturation

Oocyte maturation, fertilization, and early embryonic development occur in the absence of gene transcription. Therefore, it is critical to understand at a global level the post-transcriptional events that are driving these transitions. Here, we have used a systems approach by combining polysome mRNA...

ORGANISM(S): Mus musculus

2012-01-14 | E-GEOD-35106 | biostudies-arrayexpress

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