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TranscriptomicsThe deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways [BY4741]
The function of DFNA5 remained unknown for a long time, but previous functional studies by Op de Beeck et al. (2011) revealed that DFNA5 induces a growth defect in mutDFNA5- transfected HEK293T cells, as well as other cells, leading to PCD (Op de Beeck et al., 2011). The cell death-inducing capacity...
ORGANISM(S): Saccharomyces cerevisiae 
2015-06-24 | E-GEOD-70168 | biostudies-arrayexpress
TranscriptomicsThe deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways [HEK293T]
The function of DFNA5 remained unknown for a long time, but previous functional studies by Op de Beeck et al. (2011) revealed that DFNA5 induces a growth defect in mutDFNA5- transfected HEK293T cells, as well as other cells, leading to PCD (Op de Beeck et al., 2011). The cell death-inducing capacity...
ORGANISM(S): Homo sapiens 
2015-06-24 | E-GEOD-70167 | biostudies-arrayexpress
TranscriptomicsThe deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2015-06-24 | E-GEOD-70169 | biostudies-arrayexpress
TranscriptomicsOvercoming cetuximab resistance in HNSCC: The role of AURKB and DUSP proteins
Unraveling the underlying mechanisms of cetuximab resistance in head and neck squamous cell carcinoma (HNSCC) is of major importance as many tumors remain non-responsive or become resistant. Out microarray results suggest that resistant cells still exhibit RAS-MAPK pathway signaling contributing to ...
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-61495 | biostudies-arrayexpress
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