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Computational, genomic, and proteomic approaches have been used to discover nonannotated proteincoding small open reading frames (smORFs). Some novel smORFs have crucial biological roles in cells and organisms, which motivates the search for additional smORFs. Proteomic smORF discovery methods are a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-26 | MSV000084014 | MassIVE
The purpose of this experiment was to compare differences in the transcript level between RNA samples collected from post-mortem motor cortex from healthy control patients and amyotrophic lateral sclerosis (ALS) patients that carry an expanded GGGGCC repeat mutation in the chromosome 9 open reading ...
ORGANISM(S): Homo sapiens 
The first round of translation occurs on mRNAs bound by nuclear cap-binding complex (CBC), which is composed of nuclear cap-binding protein (CBP) 80 and 20. During this round of translation, aberrant mRNAs are recognized and downregulated in abundance by nonsense-mediated mRNA decay (NMD), which is ...
ORGANISM(S): Homo sapiens 
We developed a 'Virtual Northern' method, using DNA microarrays for genome-wide systematic analysis of mRNA lengths. We used this method to measure mRNAs corresponding to 84% of the annotated open reading frames (ORFs) in the S. cerevisiae genome, with high precision and accuracy (measurement errors...
ORGANISM(S): Saccharomyces cerevisiae 
RNA-Seq reads and TopHat (Trapnell et al. Bioinformatics 2009) alignments of K562 cell-line transcriptome. These were used to validate the expression of short peptides idenitified by Mass-Spectrometry in K562 cells. K562 polyA+ RNA (Batch 1) and total RNA (batch 2) was purchased from Ambion. We use...
ORGANISM(S): Homo sapiens 
A hallmark of high-risk childhood medulloblastoma is the dysregulation of RNA translation. Currently, it is unknown whether medulloblastoma dysregulates the translation of putatively oncogenic non-canonical open reading frames. To address this question, we performed ribosome profiling of 32 medullob...
Identification of small open reading frame encoded peptides of Thermosynechococcus vestitus BP-1(2133)
ORGANISM(S): Thermosynechococcus Elongatus Bp-1 
2025-01-09 | PXD059620 |
Identification of small open reading frame encoded peptides of Synechocystis sp. PCC 6803 (6803)
ORGANISM(S): Synechocystis Sp. Pcc 6803 Substr. Kazusa 
2025-01-08 | PXD059576 |
Identification of small open reading frame encoded peptides of Picosynechococcus sp. PCC 7002 (7002)
ORGANISM(S): Synechococcus Sp. Pcc 7002 
2025-01-10 | PXD059623 |
Identification of small open reading frame encoded peptides of Nostoc sp. PCC 7120 (7120) 
ORGANISM(S): Nostoc Sp. Pcc 7120 = Fachb-418 
2025-01-09 | PXD059618 |
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