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TranscriptomicsGRHL1 acts as a tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3
Neuroblastoma is an embryonic solid tumor of neural crest origin and accounts for 11% of all cancer-related deaths in children. Novel therapeutic strategies are therefore urgently required. MYCN oncogene amplification, which occurs in 20% of neuroblastomas, is a hallmark of high risk. Here we aimed ...
ORGANISM(S): Homo sapiens 
2014-05-22 | E-GEOD-47407 | biostudies-arrayexpress
TranscriptomicsExtrinsic and Intrinsic Regulation of DOR/TRP53INP2 Expression in Mice
The objective is to relate changes in expression of DOR/TRP53INP2, a factor involved in thyroid hormone action and autophagy, to body composition in mice fed a fat (FD) or high fat diet (HFD) for 8 days and in a genetically obese mouse model. We conclude that DOR expression depends on sex, fat conte...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-32872 | biostudies-arrayexpress
TranscriptomicsCystic leukoencephalopathy without megalencephaly
The cystic leukoencephalopathy without megalencephaly has been defined as distinct autosomal-recessive syndrome of quasi-static encephalopathy with normo- or microcephaly, impaired psychomotor development and characteristic pattern on brain MRI. We identified mutations in the gene encoding the RNASE...
ORGANISM(S): Homo sapiens 
2009-06-02 | E-GEOD-11964 | biostudies-arrayexpress
ProteomicsRapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies
Escherichia coli is a major cause of blood stream and urinary tract infections. Owing to the spread of antimicrobial resistance, it is often treated with an inadequate antibiotic. With the aim to accelerate the diagnostics of this key pathogen, we used the flycode technology to generate nanobodies a...
ORGANISM(S): Escherichia coli 
2025-06-11 | PXD054264 | Pride
Lc-ms/ms Nestlink E. coli 
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