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TranscriptomicsGene expression in WT and Ikaros-deficient LSK cells
The Ikaros zink finger transcription factor is a critical regulator of the hematopietic system, and plays an important role in the regulation of the development and function of several blood cell lineages. We used microarrays to characterize how Ikaros deficieny affects global transcription in the h...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-61147 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis wild type, cop1-4, hy5-1 mutant seedlings exposed to polychromatic radiation
Seven-day-old white-light-grown wild-type, cop1-4 or hy5-1 mutant Arabidopsis seedlings were exposed for fifteen minutes to polychromatic radiation with decreasing short-wave cut-off in the UV range (WG305 = +UV-B, WG327 = -UV-B) and samples were taken 1 h after the onset of irradiation.
ORGANISM(S): Arabidopsis thaliana 
2006-08-16 | E-MEXP-557 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis response to UV-B
Seven-day-old white-light-grown Arabidopsis seedlings were exposed for 15 minutes to polychromatic radiation with decreasing short-wave cut-off in the UV range, transferred back to the standard growth chamber and samples were taken 1 and 6 hours after the start of irradiation.
ORGANISM(S): Arabidopsis thaliana 
2006-03-01 | E-MEXP-550 | biostudies-arrayexpress
GenomicsIkaros mediates gene silencing in T cells through Polycomb Repressive Complex 2
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-61149 | biostudies-arrayexpress
TranscriptomicsIkaros-induced gene expression chages upon Ikaros re-expression in the ILC87 Ikaros-deficient tumor cell line
We used microarrays to analyze gene expression changes in the Ikaros null ILC87 T cell tumor line after re-expression of Ikaros. ILC87 cells were transduced to stably express the 4-hydroxytamoxifen-inducible (4OHT) Ikaros1-ER fusion protein. ILC87-Ik1-ER cells were treated with mock (EtOH) or 4OHT f...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-72801 | biostudies-arrayexpress
GenomicsIkaros mediates gene silencing in T cells through Polycomb Repressive Complex 2 [ChIP-seq]
T cell development is accompanied by epigenetic changes that ensure the silencing of stem cell-related, and the activation of lymphocyte-specific programs. How transcription factors influence these changes remains unclear. We show that the Ikaros transcription factor interacts with the Polycomb Repr...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-61148 | biostudies-arrayexpress
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