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TranscriptomicsTime course of prion infected (RML) and globular domain ligands (POM1) in cultured organotypic cerebellar slices (COCS)
Cultured organotypic cerebellar slices were exposed for different time points with either prions (RML) versus non-infectious brain homogenate (NBH) or ligands to the globular domain of the prion protein (POM1) vs IgG We used microarrays to characterize the temporal response of two inducers prion pro...
ORGANISM(S): Mus musculus 
2015-01-22 | E-GEOD-65147 | biostudies-arrayexpress
TranscriptomicsExpression data from rat organotypic hippocampal slices lentivirally infected with shRNF10 or scramble construct
RNF10 is a synapse-to-nucleus protein messsenger regulating NMDAR-dependent gene trascription. We have charaterized the impact of the absence of RNF10 on structural synaptic plasticity. In this dataset we included expression data from homogenates of DIV14 rat organotypic hippocampal slices lentivira...
ORGANISM(S): Rattus norvegicus 
2015-06-20 | E-GEOD-69267 | biostudies-arrayexpress
GenomicsHaptoglobin and Hemopexin Redirect Heme-Driven Oxidative Stress and Neurotoxicity in Organotypic Brain Slices
Haptoglobin and Hemopexin Redirect Heme-Driven Oxidative Stress and Neurotoxicity in Organotypic Brain Slices
PRJNA1273729 | ENA
UnknownProtocol for co-culture of primary neurons and organotypic hippocampal brain slices from mice.
Not available
S-EPMC12686910 | biostudies-literature
UnknownSpreading of Aggregated α-Synuclein in Sagittal Organotypic Mouse Brain Slices.
Not available
S-EPMC8961638 | biostudies-literature
GenomicsGene expression profile at single cell level from rhesus macaque fetal brain prefrontal cortex and human organotypic dlPFC slices.
Gene expression profile at single cell level from rhesus macaque fetal brain prefrontal cortex and human organotypic dlPFC slices.
PRJNA986148 | ENA
UnknownTime lapse recording of cortical interneuron migration in mouse organotypic brain slices and explants.
Not available
S-EPMC8082162 | biostudies-literature
GenomicsRNAseq analysis of microglia isolated from treated brain slices or treated mice
RNAseq analysis of microglia isolated from treated brain slices or treated mice
PRJNA647999 | ENA
TranscriptomicsGene expression in response to axotomy in organotypical slices co-cultures
Brain slice cultures offer advantages over other in vitro methods, as they mimic numerous in vivo aspects. For most purposes, slices of the developing brain, termed organotypic slice cultures , preserve a high degree of cellular differentiation and tissue organization. The entorhino-hippocampal conn...
ORGANISM(S): Rattus norvegicus 
2011-02-25 | E-GEOD-20528 | biostudies-arrayexpress
UnknownA versatile prion replication assay in organotypic brain slices.
Not available
S-EPMC2754795 | biostudies-literature
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