Sort   by:  
 Page size 
Transcriptomicsp27Kip1 regulates cell cycle progression by modulating the expression of p21Cip1
In addition to its classical role as a CDK inhibitor, p27 also acts as a transcriptional regulator. We found that at early passages, embryonic fibroblasts from p27-/- mouse show reduced expression of genes involved in DNA replication and progress slowly through the cell cycle. These cells have high ...
ORGANISM(S): Mus musculus 
2016-06-09 | E-MTAB-2790 | biostudies-arrayexpress
TranscriptomicsRapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming
Transplantation of GABAergic interneurons (INs) can sustain long-standing benefits in animal models of epilepsy and other neurological disorders. In a therapeutic perspective, a renewable source of functional GABAergic INs is needed. Here, we identified five factors (Foxg1, Sox2, Ascl1, Dlx5 and Lhx...
ORGANISM(S): Mus musculus 
2015-12-15 | E-GEOD-74065 | biostudies-arrayexpress
UnknownVulnerability of marine megafauna to global at-sea anthropogenic threats.
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species' vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation ...
S-EPMC12856791 | biostudies-literature
Sort   by:  
 Page size