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ProteomicsGuanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies
The dNTPase activity of tetrameric SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) plays a critical role in cellular dNTP regulation. SAMHD1 also associates with stalled DNA replication forks, DNA repair foci, ssRNA, and telomeres. The above functions require...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2023-11-13 | PXD043587 | Pride
Aicardi-goutieres syndrome Dna repair Rnase Sammhd1 Hiv 
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