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UnknownEffects of Vitamin D Supplementation during the Induction and Progression of Osteoarthritis in a Rat Model.
Not available
S-EPMC3479853 | biostudies-literature
TranscriptomicsRIP-Chip analysis of the C. elegans FOG-1 and FOG-3 proteins
FOG-1/CPEB and FOG-3/Tob are the terminal regulators of the sex determination in C. elegans germ cells. CPEB and Tob proteins are both translational regulators. To investigate how FOG-1 and FOG-3 regulate germ cell sex determination we sought to identify the target mRNAs. We used transgenic epito...
ORGANISM(S): Caenorhabditis elegans 
2015-12-14 | E-GEOD-73070 | biostudies-arrayexpress
TranscriptomicsA new dataset of spermatogenic vs oogenic transcriptomes in the nematode C. elegans
The nematode Caenorhabditis elegans is an important model for studies of germ cell biology, including specification as sperm or oocyte, the meiotic cell cycle and gamete differentiation. Fundamental to those studies is a genome-level knowledge of the germline transcriptome. Here we use RNA-Seq to ...
ORGANISM(S): Caenorhabditis elegans 
2014-07-29 | E-GEOD-57109 | biostudies-arrayexpress
TranscriptomicsIdentification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [beta-catenin organoids]
There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Medi...
ORGANISM(S): Mus musculus 
2015-10-26 | E-GEOD-67847 | biostudies-arrayexpress
TranscriptomicsIdentification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [LS-174-T]
There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Medi...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-67846 | biostudies-arrayexpress
TranscriptomicsIdentification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [Colo205]
There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Medi...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-67845 | biostudies-arrayexpress
GenomicGWAS of Preterm Birth

Preterm birth (PTB, born before 37 weeks of gestation) is a leading cause of neonatal mortality and post-natal morbidity. PTB affects one in nine all live births in the U.S. Notably, the highest rate of PTB occurs among African Americans (one in six). PTB is a complex trait, likely determined by ...

phs000332 | dbGaP
UnknownVSIG4 interaction with heparan sulfates inhibits VSIG4-complement binding.
Not available
S-EPMC10426322 | biostudies-literature
UnknownBuilding a queer- and trans-inclusive microbiology conference.
Not available
S-EPMC10783533 | biostudies-literature
UnknownMulticentric randomized clinical trial to evaluate the long-term effectiveness of a motivational intervention against smoking, based on the information obtained from spirometry in primary care: the RESET study protocol.
Not available
S-EPMC4743363 | biostudies-literature
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