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TranscriptomicsMycobacterial tuberculosis infection in hypoxia-inducible factor-1alpha deficient macrophages
We herein found the strong expression of hypoxia-inducible factor-1α (HIF-1α) in tuberculosis granulomas and more rapid death of HIF-1α-conditional knockout mice than wild-type mice after M. tuberculosis infection. These results prompted us to investigate the role of HIF-1α in host defenses against ...
ORGANISM(S): Mus musculus 
2018-09-30 | E-MTAB-7244 | biostudies-arrayexpress
ProteomicsBacterial proteins encapsulated in extracellular membrane vesicles of Escherichia coli-infected macrophages
Macrophages-derived extracellular membrane vesicles (EVs), which contain proteins, lipids, metabolisms, mRNA/microRNA, and DNA, are used for signaling in cell-to-cell communications. EVs are known to increase the levels of cytokine and chemokine and promote inflammation. Our object is to identify th...
ORGANISM(S): Cellular Organisms 
2025-01-20 | PXD059569 | JPOST Repository
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