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TranscriptomicsGene expression profiles of murine Runx1;Runx3 double deficient cKit+Sca1+Lin- hematopoietic stem/progenitor cells
The RUNX genes encode for transcription factors involved in development and human disease. RUNX1 and RUNX3 are frequently associated with leukemias, yet the basis for their involvement in leukemogenesis is not fully understood. Here we show that Runx1;Runx3 double knockout (DKO) mice exhibited letha...
ORGANISM(S): Mus musculus 
2014-08-26 | E-GEOD-51107 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine hemopoietic cell survival on oligo arrays.
Deregulated cell survival programs are a classical hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta-c subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor that selectively and independently promotes cell survival. We now show that S...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18220 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine hemopoietic cell survival on cDNA arrays.
Deregulated cell survival programs are a classical hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta-c subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor that selectively and independently promotes cell survival. We now show that S...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18221 | biostudies-arrayexpress
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