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TranscriptomicsExpression data of human ES cells-derived CD34+CD43+CD45low cells (hemogenic endothelium-like cells) expanded upon overexpression of Sox17
Overexpression of transcription factor Sox17 in human ES cells-derived endothelial cells and hematopoietic cells enhances expansion of hemogenic endothelium-like cells. Human ES cells were differentiated for 6 days, 8 days or 12 days in EBs, then CD34+CD43-CD45- endothelial cells, CD34+CD43+CD45- pr...
ORGANISM(S): Homo sapiens 
2012-12-14 | E-GEOD-37348 | biostudies-arrayexpress
TranscriptomicsHoxB4 in hematopoietic stem cells
Ectopic expression of homeodomain transcription factor HoxB4 in mouse ES cells enhances in vitro development of hematopoietic stem cells (HSCs). Mouse ES cells were differentiated for 6 days in EBs, then c-Kit+CD41+ hematopoietic precursor cells were isolated, plated onto OP9 cells, and transduced w...
ORGANISM(S): Mus musculus 
2011-05-23 | E-GEOD-26653 | biostudies-arrayexpress
TranscriptomicsCritical role of SOX17 in the hematopoietic development from human embryonic stem cells
Human embryonic stem cells (hESCs) are a powerful tool for modeling regenerative therapy. To search for the genes that promote hematopoietic development from human pluripotent stem cell, we overexpressed a list of hematopoietic regulator genes in human pluripotent stem cell-derived CD34+CD43- endoth...
ORGANISM(S): Homo sapiens 
2012-12-14 | E-GEOD-38156 | biostudies-arrayexpress
TranscriptomicsChIP-on-chip data from human ES cells-derived CD34+CD43+CD45low cells (hemogenic endothelium-like cells) overexpressing 3xFLAG-Sox17-ERT
Overexpression of transcription factor Sox17 in human ES cells-derived endothelial cells enhances expansion of hemogenic endothelium-like cells. Human ES cells were differentiated for 6 days in EBs, then CD34+CD43-CD45- endothelial cells were isolated, plated onto OP9 cells, and transduced with the ...
ORGANISM(S): Homo sapiens 
2012-12-14 | E-GEOD-37528 | biostudies-arrayexpress
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