Sort   by:  
 Page size 
UnknownHLA Haplotype Validator for quality assessments of HLA typing.
HLA alleles are observed in specific haplotypes, due to Linkage Disequilibrium (LD) between particular alleles. Haplotype frequencies for alleles in strong LD have been established for specific ethnic groups and racial categories. Application of high-resolution HLA typing using Next Generation Seque...
S-EPMC4828295 | biostudies-literature
UnknownChallenges for the standardized reporting of NGS HLA genotyping: Surveying gaps between clinical and research laboratories.
Next generation sequencing (NGS) is being applied for HLA typing in research and clinical settings. NGS HLA typing has made it feasible to sequence exons, introns and untranslated regions simultaneously, with significantly reduced labor and reagent cost per sample, rapid turnaround time, and improve...
S-EPMC8545853 | biostudies-literature
UnknownHLA alleles and haplotypes observed in 263 US families.
The 17th International HLA and Immunogenetics Workshop (IHIW) conducted a project entitled "The Study of Haplotypes in Families by NGS HLA". We investigated the HLA haplotypes of 1017 subjects in 263 nuclear families sourced from five US clinical immunogenetics laboratories, primarily as part of the...
S-EPMC6773484 | biostudies-literature
UnknownQuality control project of NGS HLA genotyping for the 17th International HLA and Immunogenetics Workshop.
The 17th International HLA and Immunogenetics Workshop (IHIW) organizers conducted a Pilot Study (PS) in which 13 laboratories (15 groups) participated to assess the performance of the various sequencing library preparation protocols, NGS platforms and software in use prior to the workshop. The orga...
S-EPMC6446570 | biostudies-literature
Sort   by:  
 Page size