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UnknownIncremental value of serum neurofilament light chain and glial fibrillary acidic protein as blood-based biomarkers for predicting functional outcome in severe acute ischemic stroke.
Not available
S-EPMC11418447 | biostudies-literature
TranscriptomicsTumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase
Deregulated expression of MYC is a driver of colorectal carcinogenesis, necessitating novel strategies to inhibit MYC function. The ubiquitin ligase HUWE1 (HECTH9, ARFBP1, MULE) associates with both MYC and the MYC-associated protein MIZ1. We show here that HUWE1 is required for growth of colorecta...
ORGANISM(S): Homo sapiens 
2014-10-21 | E-GEOD-59223 | biostudies-arrayexpress
GenomicsThe SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation
The activating E2F-transcription factors are best known for their dependence on the Retinoblastoma protein and their role in cellular proliferation. E2F3 is uniquely amplified in specific human tumours where its expression is inversely correlated with the survival of patients. Here, E2F3 interaction...
ORGANISM(S): Mus musculus 
2011-12-19 | E-GEOD-33791 | biostudies-arrayexpress
UnknownN-glycosylation Regulates Intrinsic IFN-γ Resistance in Colorectal Cancer: Implications for Immunotherapy.
Not available
S-EPMC10009756 | biostudies-literature
TranscriptomicsGeneration of highly tumorigenic cells from N-RAS61K-induced senescent cells
Activation of oncogene signaling in primary cells generally results in cellular senescence. This process is not only considered to be tumor-protective, but also irreversible. However, if senescence induction can be circumvented, e.g. by additional genetic or epigenetic changes, tumor progression oc...
ORGANISM(S): Mus musculus 
2014-01-20 | E-GEOD-27010 | biostudies-arrayexpress
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