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TranscriptomicsTranscription profiling of mouse ovaries lacking Foxl2, Wnt4 or Kit and wild type ovaries and testes
Comparison of Foxl2-null ovaries to wildtype ovaries, ovaries lacking Wnt4 or Kit, or testes, throughout mouse development. The goal of this study was to identify early Foxl2 target genes as well as other ovarian, anti-testis genes that may act independently of Foxl2. Experiment Overall Design: We s...
ORGANISM(S): Mus musculus 
2009-07-05 | E-GEOD-12905 | biostudies-arrayexpress
TranscriptomicsFoxl2 functions throughout mouse ovary development
This SuperSeries is composed of the following subset Series: GSE12905: Foxl2 functions in sex determination and histogenesis throughout mouse ovary development, analyzed by Affymetrix arrays GSE12942: Foxl2 functions in sex determination and histogenesis throughout mouse ovary development, analyzed ...
ORGANISM(S): Mus musculus 
2010-05-17 | E-GEOD-12989 | biostudies-arrayexpress
TranscriptomicsConstitutively Active Foxo3 in Oocytes Preserves Ovarian Reserve in Mice
During female reproductive life, the reserve of ovarian follicles is reduced by maturation and atresia until menopause ensues. Foxo3 is required to maintain the ovarian reserve in mice. We asked if overexpression of a constitutively active FOXO3 protein can increase long-lasting ovarian reproductive...
ORGANISM(S): Mus musculus 
2013-06-08 | E-GEOD-45389 | biostudies-arrayexpress
TranscriptomicsFoxl2 functions in sex determination and histogenesis throughout mouse ovary development, analyzed by Agilent arrays
Partial loss of function of the transcription factor FOXL2 leads to premature ovarian failure in women. In animal models, Foxl2 is required for maintenance, and possibly induction, of female sex determination independently of other critical genes, i.e., Rspo1 and Wnt4. Here we report expression prof...
ORGANISM(S): Mus musculus 
2010-05-17 | E-GEOD-12942 | biostudies-arrayexpress
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