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UnknownBet v 1-independent sensitization to major allergens in Fagales pollen: Evidence at the T-cell level.

Background

In birch-dominated areas, allergies to pollen from trees of the order Fagales are considered to be initiated by the major birch pollen allergen Bet v 1. However, the sensitizing activity of Bet v 1-homologs in Fagales pollen might be underestimated. Allergen-specific T-cells are c...
S-EPMC11497339 | biostudies-literature
UnknownInvestigation of Sensitization Potential of the Soybean Allergen Gly m 4 by Using Caco-2/Immune Cells Co-Culture Model.
The soybean allergen Gly m 4 is known to cause severe allergic reactions including anaphylaxis, unlike other Bet v 1 homologues, which induce mainly local allergic reactions. In the present study, we aimed to investigate whether the food Bet v 1 homologue Gly m 4 can be a sensitizer of the immune sy...
S-EPMC8234232 | biostudies-literature
UnknownTwo-dimensional high-throughput on-cell screening of immunoglobulins against broad antigen repertoires.
Identifying high-affinity antibodies in human serum is challenging due to extremely low number of circulating B cells specific to the desired antigens. Delays caused by a lack of information on the immunogenic proteins of viral origin hamper the development of therapeutic antibodies. We propose an e...
S-EPMC11237129 | biostudies-literature
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