Sort   by:  
 Page size 
Previous high throughput gene expression profiling combined with a HCT116 colon cancer tumor spheroid-based drug-screening assay identified context-dependent treatment responses to OXPHOS inhibitors resulting in a shunting towards the mevalonate pathway. To complement these findings with a character...
ORGANISM(S): Homo sapiens (Human) 
2020-07-29 | PXD016495 | Pride
Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared to their European American (EA) counterparts, but the molecular mechanism underlying differences are unknown. . Thus, we performed proteomics analysis of AA and EA BLCA and identified higher mitochondrial OXPHOS spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-08 | MSV000095559 | MassIVE
Mitochondrial OXPHOS restricts SARS-CoV-2 replication
OXPHOS Promotes Apoptotic Resistance and Persistence in T­H17 cells
During acute oxidative phosphorylation (OXPHOS) dysfunction, the reverse activity of succinate dehydrogenase (Complex II) maintains the redox state of the Coenzyme Q pool by utilizing either fumarate or oxygen as terminal electron acceptors. The tendency for one over another has been suggested to be...
ORGANISM(S): Homo sapiens (Human) 
2025-06-06 | PXD064653 | Pride
Type 1 interferons (IFNs) induce complex responses that can be beneficial or deleterious, depending on context. Greater understanding of the mechanisms of action of these cytokines could allow new therapeutic approaches. We found that type 1 IFNs induced changes in cellular metabolism that were cr...
ORGANISM(S): Mus musculus 
This a model from the article: Adenine nucleotide-creatine-phosphate module in myocardial metabolic system explains fast phase of dynamic regulation of oxidative phosphorylation. van Beek JH. Am J Physiol Cell Physiol 2007 Sep;293(3):C815-29 17581...
2005-01-01 | MODEL1006230027 | BioModels
During acute oxidative phosphorylation (OXPHOS) dysfunction, the reverse activity of succinate dehydrogenase (Complex II) maintains the redox state of the Coenzyme Q pool by utilizing either fumarate or oxygen as terminal electron acceptors. The tendency for one over another has been suggested to be...
ORGANISM(S): Homo sapiens (Human) 
2025-06-06 | PXD064675 | Pride
Sort   by:  
 Page size