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MetabolomicsComputational mass spectrometry accelerates C=C position-resolved untargeted lipidomics using oxygen attachment dissociation
Mass spectrometry-based untargeted lipidomics has revealed the lipidome atlas of living organisms at the molecular species level. Despite the double bond (C=C) position being a crucial factor for enzyme preference, cellular membrane milieu, and biological activity, the C=C defined structures have no...
2022-11-09 | MTBLS5861 | MetaboLights
ModelsDevelopment of agent-based models describing the response of Escherichia coli to changes in oxygen availability
Development of agent-based models describing the response of Escherichia coli to changes in oxygen availability
2009-10-26 | 18 | FAIRDOMHub
TranscriptomicsInfluence of oxygen limitation, absence of the cytochrome bc1 complex and low pH on global gene expression in Gluconobacter oxydans 621H using DNA microarray technology
The genome-wide transcriptional responses of the strictly aerobic -proteobacterium Gluconobacter oxydans 621H to oxygen limitation, to the absence of the cytochrome bc1 complex, and to low pH were studied using DNA microarray analyses. Oxygen limitation caused expression changes of 486 genes, repres...
ORGANISM(S): Gluconobacter oxydans 621H 
2012-03-23 | E-GEOD-34294 | biostudies-arrayexpress
ProteomicsOxygen Toxicity Causes Cyclic Damage by Destabilizing Specific Fe-S Cluster-Containing Protein Complexes
Oxygen is toxic across all three domains of life. Yet, the underlying molecular mechanisms remain largely unknown. Here, we systematically investigate the major cellular pathways affected by excess molecular oxygen. We find that hyperoxia destabilizes a specific subset of Fe-S cluster (ISC)-containi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-05 | MSV000091206 | MassIVE
MetabolomicsErythrocyte adenosine A2B receptor-mediated AMPK activation: Counteracting CKD by promoting oxygen delivery
Not available
ORGANISM(S): Mus musculus 
ST001153 | MetabolomicsWorkbench
TranscriptomicsLow oxygen responsive small RNAs in Arabidopsis
Low-oxygen stress associated with natural phenomena such as waterlogging, results in widespread transcriptome changes and a metabolic switch from aerobic respiration to anaerobic fermentation. High-throughput sequencing of small RNA libraries obtained from low-oxygen stressed and control root tissue...
ORGANISM(S): Arabidopsis thaliana 
2009-09-30 | E-GEOD-16971 | biostudies-arrayexpress
GenomicsDerivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
The presence of two active X chromosomes (XaXa) is a hallmark of the ground state of pluripotency specific to murine embryonic stem cells (ESCs). Human ESCs invariably exhibit signs of X chromosome inactivation (XCI) and are considered developmentally more advanced than their murine counterparts. W...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-21141 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type, fixJ, fixK and fixK-like mutant strains of Sinorhizobium meliloti cultured at different oxygen levels
Comparative transcriptome analysis in various oxygen concentrations of wild type and fixJ mutant strains of Sinorhizobium meliloti.
ORGANISM(S): Sinorhizobium meliloti 
2006-08-10 | E-TABM-121 | biostudies-arrayexpress
TranscriptomicsHigh oxygen prevents fetal lethality due to lack of catecholamines
The catecholamine norepinephrine is required for fetal survival, but its essential function is unknown. When catecholamine-deficient [tyrosine hydroxylase (Th) null] mouse fetuses die at E13.5-E14.5, they resemble wild type fetuses exposed to hypoxia. They exhibit bradycardia (28% reduction in hear...
ORGANISM(S): Mus musculus 
2008-06-03 | E-GEOD-10341 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis thaliana (Ler) rosette leaves after the release of singlet oxygen inside plastids
We used the flu mutant of Arabidopsis to detail gene expression in response to singlet oxygen. The conditional flu mutant of Arabidopsis accumulates excess protochlorophyllide in the dark within chloroplast membranes that upon illumination acts as a photosensitizer and generates singlet oxygen. Imme...
ORGANISM(S): Arabidopsis thaliana 
2008-04-05 | E-GEOD-10876 | biostudies-arrayexpress
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