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ProteomicsHDX-MS analysis of the full human proteasome in complex with regulators
Hydrogen-Deuterium eXchange coupled to Mass Spectrometry (HDX-MS) analysis to investigate the solvent accessibility of the full human 20S proteasome alone or in complex with PA28 regulatory particles. Our work reveals a reciprocal crosstalk between the inner and outer rings of the human 20S proteaso...
ORGANISM(S): Homo sapiens (Human) 
2020-09-11 | PXD018921 | Pride
: proteasome Hydrogen-deuterium exchange Immunoproteasome Structural biology Pa28 alpha beta Bioinformatics Pa28 gamma Structural ms 
UnknownPA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo.
Not available
S-EPMC3100532 | biostudies-literature
UnknownADP-Ribosylation Regulates the Signaling Function of IFN-γ.
Not available
S-EPMC7983947 | biostudies-literature
UnknownProteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation.
Not available
S-EPMC2265109 | biostudies-literature
UnknownComparative transcriptome analysis of MDBK cells reveals that BoIFN-γ augmented host immune responses to bovine herpesvirus 1 infection.
Not available
S-EPMC9396027 | biostudies-literature
UnknownDecreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression.
Not available
S-EPMC7047544 | biostudies-literature
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