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TranscriptomicsAneuploidy, oncogene amplification, and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells [CGH]
Human epithelial cancers are defined by a recurrent distribution of specific chromosomal aneuploidies. In our model system, mouse bladder and kidney epithelial cells spontaneously immortalize, transform and become tumorigenic after prolonged culture. We assessed genome and transcriptome alterations...
ORGANISM(S): Mus musculus 
2013-03-14 | E-GEOD-45128 | biostudies-arrayexpress
TranscriptomicsAneuploidy, oncogene amplification, and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-03-14 | E-GEOD-45129 | biostudies-arrayexpress
Genomicsena-DATASET-OSUCCC-31-10-2013-20:19:37:619-31 - samples
Whole genome sequencing data from Illumina platform were generated using 10 human cancer cell lines and 2 primary tumor samples. Nine of these samples contained fragments of human papillomavirus (HPV).
EGAD00001000691 | EGA
GenomicsGenome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
Genomic instability is a hallmark of human cancers, including the 5% caused by human papillomavirus (HPV). Here we report a striking association between HPV integration and adjacent host genomic structural variation in human cancer cell lines and primary tumors. Whole genome sequencing revealed HPV ...
EGAS00001000599 | EGA
GenomicsHPV Virome Consortium Data Access Committee
Data Access Committee EGAC00001000141
EGAC00001000141 | EGA
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