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ProteomicsQuantitative LC-MS/MS Proteomics of paediatric human liver microsomes
We report label-free quantification of xenobiotic metabolizing enzymes (XME), transporters, redox enzymes, proteases and nucleases in 20 human liver microsomal samples. More than 3500 proteins were identified and quantified. These data can be used in physiologically based pharmacokinetic models to ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020844 | Pride
Human Quantitative proteomics Paediatric livers Lc-ms/ms 
ProteomicsQuantitative LC-MS/MS Proteomics of paediatric human liver microsomes (set 2)
We report label-free quantification of xenobiotic metabolizing enzymes (XME), transporters, redox enzymes, proteases and nucleases in 24 human liver microsomal samples. More than 3500 proteins were identified and quantified. These data can be used in physiologically based pharmacokinetic models to ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020939 | Pride
Human Quantitative proteomics Paediatric livers Lc-ms/ms 
ProteomicsQuantitative LC-MS/MS Proteomics of paediatric biliary atresia human liver microsomes
We report label-free quantification of xenobiotic metabolizing enzymes (XME), transporters, redox enzymes, proteases and nucleases in 25 human liver microsomal samples, taken from patients with biliary atresia. Nearly 3500 proteins were identified and quantified. These data can be used in physiolog...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020974 | Pride
Human Quantitative proteomics Biliary atresia Paediatric livers Lc-ms/ms 
UnknownHistopathology of livers in patients with congenital portosystemic shunts (Abernethy malformation): a case series of 22 patients.
Not available
S-EPMC6323085 | biostudies-literature
UnknownReference values for shear wave elastography, shear wave dispersion and attenuation imaging in healthy paediatric livers.
Not available
S-EPMC12831688 | biostudies-literature
UnknownChimeric Antigen Receptor-modified T cells targeting EphA2 for the immunotherapy of paediatric bone tumours.
Not available
S-EPMC8057949 | biostudies-literature
TranscriptomicsHuman fetal liver, skin and kidney single cell transcriptome data
This is a droplet-based single cell transcriptome data set from 13 human fetal livers (6-18 PCW) and 8 skin and kidney samples (6-12 PCW). It includes 199,642 cells with a mean detected gene number of 3000.
ORGANISM(S): Homo sapiens 
2019-10-11 | E-MTAB-7407 | biostudies-arrayexpress
TranscriptomicsThe regenerative response in the pig liver remnant varies with the degree of resection and rise in portal pressure.
Following parenchymal loss, the liver regenerates restoring normal mass and metabolic function. Prevailing theories on triggering events leading to regeneration include humoral, metabolic and flow-mediated mechanisms, the latter emphasizing the importance of shear stress mediated nitric oxide (NO) r...
ORGANISM(S): Sus scrofa 
2008-01-14 | E-GEOD-6860 | biostudies-arrayexpress
TranscriptomicsRNAseq of sorted Kupffer cells during ulcerative colitis
Ulcerative colitis impact on Kupffer cell homeostasis was assessed using transcriptional analysis. Kupffer cells were sorted from the livers of mice treated with dextran sodium sulphate for 7 days. Total RNA preparation was performed on 20,000 sorted Kupffer cells.
ORGANISM(S): Mus musculus 
2026-09-02 | E-MTAB-15568 | biostudies-arrayexpress
TranscriptomicsOntogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene-driven myeloid leukemia - scRNAseq - 2
Paediatric cancers present specific genetic alterations, however the principles underlying their differences to adult cancers are yet unclear. Poor prognosis paediatric myeloid leukaemia fusion oncogenes represent clinically-relevant models to investigate age-specific tumorigenesis. Here, we establi...
ORGANISM(S): Mus musculus 
2019-10-15 | E-MTAB-8360 | biostudies-arrayexpress
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