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MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
MetabolomicsHepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Despite intensive research and constant medical progress, sepsis remains one of the most urgent unmet medical needs of today. Most studies have been focused on the inflammatory component of the disease, however, recent advances support the notion that sepsis is accompanied by extensive metabolic ...

2020-01-10 | MTBLS1386 | MetaboLights
UnknownBRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families.
Not available
S-EPMC2409651 | biostudies-literature
UnknownActive enhancer and chromatin accessibility landscapes chart the regulatory network of primary multiple myeloma.
Not available
S-EPMC6014038 | biostudies-literature
TranscriptomicsThe Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses
Microbiota-induced cytokine responses participate in gut homeostasis, but the cytokine balance at steady-state and the role of individual bacterial species in setting the balance remain elusive. Using gnotobiotic mouse models, we provide a systematic analysis of the role of microbiota in the inducti...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18056 | biostudies-arrayexpress
UnknownReduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy.
Not available
S-EPMC11062611 | biostudies-literature
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