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ProteomicsMultitiered proteome analysis displays the hyperpermeability of the rheumatoid synovial compartment for plasma proteins
Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and cartilage/bone destruction. RA affects the synovial joints, the synovial lining and consequently the permeability of the synovium. As the latter is of central relevance for the distribution of systemically delivered therapeutics ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-21 | PXD054336 | Pride
Paired plasma and synovial fluid proteomics  repertoire profiling  igg1  acpa 
UnknownMultitiered Proteome Analysis Displays the Hyperpermeability of the Rheumatoid Synovial Compartment for Plasma Proteins.
Not available
S-EPMC11821404 | biostudies-literature
UnknownFc Proteoforms of ACPA IgG Discriminate Autoimmune Responses in Plasma and Synovial Fluid of Rheumatoid Arthritis Patients and Associate with Disease Activity.
Not available
S-EPMC12005756 | biostudies-literature
ProteomicsProteomic profiling of Extracellular Vesicles in synovial fluid and plasma from Oligoarticular Juvenile Idiopathic Arthritis patients reveals novel immunopathogenic biomarkers
New early low-invasive biomarkers are highly demanded for the management of Oligoarticular Juvenile Idiopathic Arthritis (OJIA), the most common chronic pediatric rheumatic disease in Western countries and a leading cause of disability. Despite recent significant advances in OJIA treatment, a high p...
ORGANISM(S): Homo sapiens (Human) 
2023-07-05 | PXD039166 | Pride
Proteomics Mass spectrometry Ojia Extracellular vesicles Plasma Synovial fluid 
UnknownProteomic profiling of extracellular vesicles in synovial fluid and plasma from Oligoarticular Juvenile Idiopathic Arthritis patients reveals novel immunopathogenic biomarkers.
Not available
S-EPMC10186353 | biostudies-literature
UnknownIgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence.
Not available
S-EPMC4245247 | biostudies-literature
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