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TranscriptomicsMorphological, electrophysiological and transcriptomic profiling of single neurons using Patch-seq
The mammalian neocortex is a layered sheet of neural tissue that mediates complex cognitive processes including perception and cognition. Despite its importance, we still lack detailed knowledge of the cellular components of the neocortex. Integrating morphological, electrophysiological and molecula...
ORGANISM(S): Mus musculus 
2016-01-25 | E-MTAB-4092 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq analysis of human pancreas from healthy individuals and type 2 diabetes patients
We used single-cell RNA-sequencing to generate transcriptional profiles of endocrine and exocrine cell types of the human pancreas. Pancreatic tissue and islets were obtained from six healthy and four T2D cadaveric donors. Islets were cultured and dissociated into single-cell suspension. Viable indi...
ORGANISM(S): Homo sapiens 
2016-09-22 | E-MTAB-5061 | biostudies-arrayexpress
TranscriptomicsWhole-islet RNA-sequencing analysis of human pancreas from healthy individuals and type 2 diabetes patients
We performed whole-islet RNA-sequencing of human pancreatic islets from healthy and T2D individuals in order to compare the expression data to the corresponding single-cell RNA-sequencing data from the same donors (related single-cell study: Single-cell analysis of human pancreas and T2D, deposited ...
ORGANISM(S): Homo sapiens 
2016-09-22 | E-MTAB-5060 | biostudies-arrayexpress
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