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TranscriptomicsTranscript atlases reveal that artery tertiary lymphoid organs but not secondary lymphoid organs control key steps of atherosclerosis T cell immunity in aged apoe-/- mice.
Tertiary lymphoid organs (TLOs) emerge in response to nonresolving inflammation but their roles in adaptive immunity remain unknown. Here, we explored artery TLOs (ATLOs) to delineate atherosclerosis T cell responses in apoe-/- mice during aging. Though the T cell repertoire showed systemic age-asso...
ORGANISM(S): Mus musculus 
2013-10-30 | E-GEOD-40156 | biostudies-arrayexpress
TranscriptomicsTracking the fate of pathogenic CD4 T helper cells in vivo.
Inflammation is a beneficial host response to infection, but it also contributes to inflammatory disease if unregulated. The Th17 lineage of T helper (Th) cells can cause severe human inflammatory diseases. These cells exhibit both instability (i.e., they can cease to express their signature cytoki...
ORGANISM(S): Mus musculus 
2015-04-25 | E-GEOD-68242 | biostudies-arrayexpress
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
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