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Unknown(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Not available
S-EPMC4434478 | biostudies-literature
UnknownDiscovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models.
Not available
S-EPMC4025649 | biostudies-literature
UnknownDiscovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.
Not available
S-EPMC4948009 | biostudies-literature
UnknownCoupling of sea level and tidal range changes, with implications for future water levels.
Not available
S-EPMC5717176 | biostudies-literature
UnknownDiscovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist.
Not available
S-EPMC4007689 | biostudies-literature
UnknownProteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration.
Not available
S-EPMC8439011 | biostudies-literature
UnknownDiscovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator.
Not available
S-EPMC4027137 | biostudies-literature
UnknownAbsence of West Nile and Usutu Virus Persistence in Overwintering Mosquitoes in Northeastern France: Insights from Cold-Season Surveillance.
Not available
S-EPMC12474421 | biostudies-literature
ProteomicsDeep Multilayer Tissue Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression, human data
The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-17 | MSV000096123 | MassIVE
TranscriptomicsscRNA-seq of human trophoblast organoids EVT-differentiated in 21%, 8%, and 3% oxygen
Placental development occurs in a low oxygen environment, yet how oxygen tension instructs differentiation of progenitor cytotrophoblasts (CTB) along the extravillous versus villous pathways remains incompletely understood. In particular, the role of low oxygen in early extravillous trophoblast (EVT...
ORGANISM(S): Homo sapiens 
2026-09-01 | E-MTAB-16328 | biostudies-arrayexpress
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