Sort   by:  
 Page size 
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
UnknownThe long non-coding RNA SAMMSON is essential for uveal melanoma cell survival.
Not available
S-EPMC8724009 | biostudies-literature
Transcriptomicswnt in human embryonic carcinoma cells
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway. Results We have identified target genes of Wnt signaling using microarray technology and human embryonal carcinom...
ORGANISM(S): Homo sapiens 
2005-09-08 | E-GEOD-3262 | biostudies-arrayexpress
UnknownAKT Inhibition in Solid Tumors With AKT1 Mutations.
Not available
S-EPMC5501365 | biostudies-literature
ModelsStokes2020 - Antibiotics discovery using deep learning approach.
Based on a simple E.coli growth inhibition assay, the authors trained a model capable of identifying antibiotic potential in compounds structurally divergent from conventional antibiotic drugs. One of the predicted active molecules, Halicin (SU3327), was experimentally validated in vitro and in vivo...
2024-04-22 | MODEL2404080001 | BioModels
Machine Learning Model Ersilia 
ModelsStokes2020 - Antibiotics discovery using deep learning approach (Antiviral implementation)
This model was developed to support the early efforts in the identification of novel drugs against SARS-CoV2. It predicts the probability that a small molecule inhibits SARS-3CLpro-mediated peptide cleavage. It was developed using a high-throughput screening against the 3CL protease of SARS-CoV1, as...
2024-05-08 | MODEL2405080006 | BioModels
Machine Learning Model Ersilia 
TranscriptomicsTranscription profiling of wnt in human embryonic carcinoma cells
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway. Results We have identified target genes of Wnt signaling using microarray technology and human embryonal carcinom...
ORGANISM(S): Homo sapiens 
2005-09-02 | E-SMDB-1827 | biostudies-arrayexpress
GenomicsEGAS00001000262-sc-20140722b - samples
Whole Genome Sequencing Illumina HiSeq data from 20 men with prostate cancer. 20 samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). These were submitted for use in the ICGC Pan-Cancer Analysis of Wh...
EGAD00001000892 | EGA
UnknownA biogeographical appraisal of the threatened South East Africa Montane Archipelago ecoregion.
Not available
S-EPMC10933300 | biostudies-literature
TranscriptomicsTranscription profiling of rat metanephric mesenchyme induced to convert into nephron epithelia
During kidney development segmented epithelia of the nephron derive from progenitor cells in the metanephric mesenchyme after induction by secreted molecules from the ureteric bud. We have identified three distinct inductive activities from a ureteric bud cell line. These include leukemia inhibitory...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5478 | biostudies-arrayexpress
Sort   by:  
 Page size