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ProteomicsQuantitative proteomics and bioinformatics analyses reveal the mechanism of pan-aurora kinase inhibitor tozasertib in neuroblastoma
Neuroblastoma is the third most common pediatric cancer and is responsible for approximately 15% of all childhood cancer deaths (Maris & Matthay, 1999). In our analysis, we found that poor patient survival with increasing mRNA expression level of AURKA and AURKB in Mycn-amplified neuroblastoma. In t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-09-30 | PXD007640 | Pride
Neuroblastoma/ tozasertib/ itraq/ metabolite/ aurora kinase inhibitor. 
UnknownElucidation of the anti-lung cancer mechanism of Juan-Liu-San-Jie prescription based on network pharmacology and experimental validation.
Not available
S-EPMC10407049 | biostudies-literature
TranscriptomicsTranscription profiling of Mycobacterium avium subspecies paratuberculosis Types I, II and III genomes by pan-genome microarray analysis
Data is also available from http://bugs.sgul.ac.uk/E-BUGS-69
ORGANISM(S): Mycobacterium avium 
2009-01-16 | E-BUGS-69 | biostudies-arrayexpress
UnknownAge-Related Dynamics of Fecal Microbiota in the Captive Chimpanzee (<i>Pan troglodytes</i>).
Not available
S-EPMC12445987 | biostudies-literature
MetabolomicsMulti-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Carotenoids; UPLC-DAD assay)

Grapes are one of the major fruit crops and they are cultivated in many dry environments. This study comprehensively characterizes the metabolic response of grape berries exposed to water deficit at different developmental stages. Increases of proline, branched-chain amino acids, phenylpropanoids...

2021-08-16 | MTBLS984 | MetaboLights
TranscriptomicsCapture-C experiments on auxin treated control (E14-Tir) and Scc1-AID, Ring1b-AID, Ring1b-AID-Scc1-AID and CTCF-AID (with and without a 6-hour auxin treatment) cells
The aim of the experiment was to gain a higher resolution for specific regions of interest to complement the Hi-C results. Capture-C experiments were performed on four-inducible degrons for Scc1, Ringb, Ring1b-Scc1 and CTCF, and Tir1 control, always in triplicates (three biological replicates per co...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7840 | biostudies-arrayexpress
UnknownInterpretable multimodal deep learning for real-time pan-tissue pan-disease pathology search on social media.
Not available
S-EPMC7581495 | biostudies-literature
ProteomicsDPHL v2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins
we generated DPHL v2 from 1608 DDA-MS data acquired using Orbitrap mass spectrometers. The data included 586 DDA-MS newly acquired from 17 tissue types, while 1022 files were derived from DPHL v1. DPHL v2 thus comprises data from 24 sample types, including several cancer types . We generated four va...
ORGANISM(S): Homo Sapiens 
2023-01-18 | PXD039313 |
UnknownA U.S. Pharmacopeia (USP) overview of Pan American botanicals used in dietary supplements and herbal medicines.
Not available
S-EPMC11392873 | biostudies-literature
ModelsNogales2020 - Genome-scale metabolic network of Pseudomonas putida (iJN1462)
iJN1462 (i) incorporates several hundred additional genes and associated reactions resulting in new predictive capabilities, including new nutrients supporting growth; (ii) was validated by in vivo growth screens that included previously untested carbon (48) and nitrogen (41) sources; (iii) yielded ...
2024-10-15 | BIOMD0000001093 | BioModels
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