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MetabolomicsMetabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)

This article contains mass spectrometry (MS) data investigating small molecule changes as an effect of a triple peroxisome proliferator-activated receptor (PPAR-pan) agonist GW625019 in the liver as described in the manuscript “PPAR-pan Activation Induces Hepatic Oxidative Stress and Lipidomic Re...

2016-05-13 | MTBLS303 | MetaboLights
MetabolomicsIntegrated Multi-omics Elucidation of the Uric Acid Degradation Pathway in Limosilactobacillus fermentum M5e

Hyperuricemia is a growing global health concern associated with gout, renal diseases, and cardiovascular disorders. Current pharmacotherapies are often limited by side effects, underscoring the need for alternative strategies. In this study, we isolated Limosilactobacillus fermentum M5...

2026-01-26 | MTBLS13223 | MetaboLights
TranscriptomicsGene expression changes induced by the pan-PIM inhibitor ETP-39010 in 4 peripheral T cell lymphoma cell lines
Peripheral T cell lymphoma (PTCL) is a very aggressive disease which currently lacks efficient targeted therapy. New therapeutic strategies are needed to improve the very poor outcome of these patients. In these study we hypothesized that PIM kinases could be of therapeutic value in PTCL because we ...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-42595 | biostudies-arrayexpress
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate
Background & Aims: Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesized that spirul...
2026-06-30 | MTBLS14901 | MetaboLights
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate
Background & Aims: Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesized that spirul...
2026-06-30 | MTBLS14903 | MetaboLights
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate

Background & Aims:

Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesize...

2026-01-12 | MTBLS13657 | MetaboLights
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate

Background & Aims:

Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesize...

2026-01-11 | MTBLS13653 | MetaboLights
TranscriptomicsMethanobrevibacter smithii expression profiling
This SuperSeries is composed of the following subset Series: GSE25408: The pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii GSE25535: Expression data from an in vitro growth of Methanobrevibacter smithii PS Refer to individual Series
ORGANISM(S): Methanobrevibacter smithii ATCC 35061 
2011-11-07 | E-GEOD-25537 | biostudies-arrayexpress
TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data]
Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29705 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1 oxygen, light and phoR perturbation
A 50ml culture of Halobacterium NRC-1 knockout strain delta-ura3 with additional in-frame gene deletion of phoR was grown to mid-log phase in a 125ml flask in rich media under varying oxygen and light conditions. Low and high light indicate growth in a painted flask versus growth in a standard clea...
ORGANISM(S): Halobacterium sp. NRC-1 
2008-01-03 | E-GEOD-7730 | biostudies-arrayexpress
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