Panc-1 cells - OmicsDI

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Disease

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Instrument Platform

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Shanghai Genefund Biotech Co., Ltd Illumina NovaSeq 6000 (2)
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CHEBI ID

CHEBI:16958 (3)
CHEBI:7916 (3)
CHEBI:175901 (2)
CHEBI:142440 (2)
CHEBI:73027 (2)
CHEBI:75062 (2)
CHEBI:20129 (2)
CHEBI:19702 (2)
CHEBI:16709 (2)
CHEBI:16856 (2)
CHEBI:18237 (2)
CHEBI:15346 (2)
CHEBI:17126 (2)
CHEBI:27570 (2)
CHEBI:20607 (2)
CHEBI:68433 (2)
CHEBI:21440 (2)
CHEBI:19065 (2)
CHEBI:21891 (2)
CHEBI:16335 (2)
CHEBI:27266 (2)
CHEBI:28946 (2)
CHEBI:24813 (2)
CHEBI:29016 (2)
CHEBI:15351 (2)
CHEBI:16919 (2)
CHEBI:15354 (2)
CHEBI:16020 (2)
CHEBI:143284 (1)
CHEBI:143282 (1)

Metabolite Name

S-(1,2-dicarboxyethyl)glutathione (2)
Pantothenate (2)
Beta-alanine (2)
N6-Threonyl-carbamoyl-adenosine (1)
1-Ribosyl-imidazolenicotinamide (1)
N2,N7-Dimethylguanosine (1)
N2,N2,N7-Trimethylguanosine (1)
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (1)
4-quinolinecarboxylic acid (1)
Phosphatidylcholine 38:1 (1)
5-Deoxy-5-methylthioadenosine (1)
Phosphatidylcholine 34:1 (1)
Malonyl-coa (1)
N1-Methylguanosine (1)
Fructose 1,6-bisphosphate (1)
P-Vinylbiphenyl (1)
Oxalic acid-guanidine (1/1) (1)
1,6-di-o-phosphonohex-2-ulofuranose (1)
Dibutyl terephthalate (1)
(R)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid (1)
L-Glutarylcarnitine (1)
4,4'-Methylenediphenol (1)
Dehydrofelodipine (1)
U-0126 (1)
Methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-thiohexopyranoside (1)
N'-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]-4-nitrobenzohydrazide (1)
1-(3-Isocyanatophenyl)-5-(methylsulfanyl)-1H-tetrazole (1)
Gly-Met-Val (1)
3-Aminopentanoic acid (1)
2-[3-Carboxy-3-(methylammonio)propyl]-L-histidine (1)

First Public Date

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2017 (8)
2015 (7)
2016 (2)

Modelling Approach

Ordinary differential equation model (2)

Study status

Not yet recruiting (1)
Recruiting (1)

Lab affiliation

State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China (3)
University at buffalo, SUNY (3)
Abbvie Bioresearch Center (2)
Biochemistry and molecular biology, Duong lab, University of British Columbia (2)
Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. (2)
Lineberger Comprehensive Cancer Center at UNC Chapel Hill (2)
Turku Centre for Biotechnology University of Turku and Åbo Akademi University Finland (2)
A2 Biotherapeutics (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Cell and Chemical Biology Leiden University Medical Center (LUMC) The Netherlands (1)
Center for Bioanalysis, Division of Chemical and Medical Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Republic of Korea (1)
Core Unit Proteomics, Berlin Institute of Health at Charite - Universitaetsmedizin Berlin and Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany (1)
Davide Ruggero, Ph.D. Professor Department of Urology, University of California San Francisco (1)
Department of Biochemistry and Molecular and Structural Biology Jozef Stefan Institute Slovenia (1)
Department of Chemistry, Imperial College London, Molecular Research Science Hub, 80 Wood Lane, London W12 0BZ, United Kingdom. The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom. (1)
Department of Laboratory Medicine and Pathology, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA (1)
Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Malaysia (1)
Department of Oncology of the Third Xiangya Hospital of Central South University (1)
Department of Pathology, Institute of Systems Biomedicine, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Peking University Health Science Center, Beijing, China (1)
Department of Pharmaceutical Sciences, University at Buffalo (1)
Department of Surgery, Key laboratory of diagnosis and Treatment of Severe Hepato-Pancreatic diseases of Zhejiang Province, Zhejiang Provincial Top Key discipline in Surgery, The First affiliated Hospital of Wenzhou Medical university, Nanbaixiang Street, Wenzhou, Zhejiang, P.R. China (1)
Department of Surgery, University of Michigan, USA. (1)
Department of System Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China. (1)
Department of oncology of the third Xiangya Hospital of Central South University (1)
Departments of Medicine (Oncology) and of Chemical and Systems Biology, Stanford School of Medicine, Stanford, CA, USA Stanford Cancer Institute, Stanford, CA, USA (1)
Depratment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. (1)
Dept. of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill (1)
Derpatment of Medical Biochemistry, Uppsala University, Uppsala, Sweden. (1)
Dipartimento di medicina Traslazionale, Università del Piemonte Orientale (1)
Département de biochimie Faculté de Médecine Université de Montréal (1)

Keyword

CAR T Cell (2)
Autologous (2)
HLA-A2 (2)
PANC (2)
T cell (1)
Carcinoembryonic Antigen (1)
Solid Tumors Expressing CEA (1)
T Cell (1)
Mesothelin (1)
MSLN (1)
Solid Tumors expressing MSLN (1)
Pancreatic (1)
Cell Therapy (1)
Gene Therapy (1)
Blocker (1)
OVCA (1)
CEA (1)

IsPrivate

False (2)

Modification

+3amu) (1)

Study type

Transcription profiling by array (65)
RNA-seq of coding RNA (12)
ChIP-seq (7)
Methylation profiling by array (3)
RNA-seq of total RNA (3)
Comparative genomic hybridization by array (2)
Interventional (2)
Transcription profiling by RT-PCR (1)
MicroRNA profiling by array (1)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (99)
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2020 (77)
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2024 (72)
2017 (65)
2016 (65)
2019 (62)
2015 (57)
2018 (53)
2014 (48)
2013 (34)
2012 (34)
2011 (24)
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2009 (12)
2010 (11)
2008 (6)
2003 (3)
2007 (2)
2005 (1)

Location

United States (2)

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PANC-1 cell differentiation

Multiple commercial microarrays for measuring genome-wide gene expression levels are currently available, including oligonucleotide and cDNA, single- and two-channel formats. This study reports on the results of gene expression measurements generated from identical RNA preparations that were obtaine...

ORGANISM(S): Homo sapiens

2007-05-15 | E-GEOD-7785 | biostudies-arrayexpress

Expression analysis of human pancreatic cancer cell lines (Capan-1, Panc-1, Panc-1+ve and Panc-1-ve) and pancreatic ductal cell line (HPDE)

Analysis of differentially expressing genes in whole genome wide analysis of aptamer SQ2 positive cells (Capan-1, Panc-1, Panc-1+ve) and SQ2 negative cells (Panc-1-ve and HPDE) Panc-1 +ve and Panc-1-ve cell lines were generated from Panc-1 cell line based upon its hetergenous binding to aptamer SQ2...

ORGANISM(S): Homo sapiens

2012-11-21 | E-GEOD-42428 | biostudies-arrayexpress

Expression data by BRD7552 treatment in PANC-1 cells

Three master regulatory transcription factors Pdx1, MafA and Ngn3 have the ability to transdifferentiate pancreatic acinar cells to insulin-producing beta cells in mice. BRD7552 was identified as a small-molecule inducer that can upregulate the expression of Pdx1 in PANC-1 cells by high-throughput q...

ORGANISM(S): Homo sapiens

2013-03-10 | E-GEOD-44946 | biostudies-arrayexpress

RNA-seq of PANC-1 cells after TGM2 KD

The PANC-1 cells were maintained on DMEM supplemented with 10% FBS, 1% penicillin-streptomycin. RNA-seq of PANC-1 cells after TGM2 KD.

ORGANISM(S): Homo sapiens

2025-01-01 | E-MTAB-14474 | biostudies-arrayexpress

Expression analysis of RNAi mediated ALPPL2 knockdown in ALPPL2 expressing Panc-1 cells (Panc-1+ve)

Analysis of differentially expressing genes in whole genome wide analysis of ALPPL2 expressing Panc-1 cells (Panc-1+ve) via siRNA mediated knockdown of ALPPL2 Panc-1 +ve and Panc-1-ve cell lines were generated from Panc-1 cell line based upon its hetergenous binding to aptamer SQ2. Detailed procedu...

ORGANISM(S): Homo sapiens

2012-11-21 | E-GEOD-42427 | biostudies-arrayexpress

cGMP inducer effect on cell line Panc-1

cGMP is well-known secound messanger involved in vascular homeostasis. However little is known the effect of cGMP inducer on mRNA expression in cancer cells. We performed microarrays to revealed the transcriptional change of a human pancreatic ductal adenocarcinoma (PDCA) cell line (Panc -1) to cGM...

ORGANISM(S): Homo sapiens

2016-09-01 | E-GEOD-66403 | biostudies-arrayexpress

ChIP-seq of PANC-1 cells using anti-H3K4me3Q5ser

The PANC-1 cells were maintained on DMEM supplemented with 10% FBS, 1% penicillin-streptomycin. ChIP-seq of PANC-1 cells using anti-H3K4me3Q5ser.

ORGANISM(S): Homo sapiens

2025-05-08 | E-MTAB-14475 | biostudies-arrayexpress

H3K4me3Q5ser ChIP-seq of H3.3 or H3.3Q5A expressing PANC-1 cells and TGM2 knockdown PANC-1 cells

H3K4me3Q5ser ChIP-seq were performed in H3.3 or H3.3Q5A expressing PANC-1 cells and TGM2 knockdown PANC-1 cells to investigate genes directly regulated by H3K4me3Q5ser.

ORGANISM(S): Homo sapiens

2025-05-08 | E-MTAB-14997 | biostudies-arrayexpress

GSK3B shRNA in Panc-1 xenografts

The Panc-1 human pancreatic cancer line (ATCC) was constructed to stably express control or GSK3B shRNA. Control or GSK3B shRNA expressing Panc-1 cells were implanted subcutaneously into the flanks of 3-5 week old, female, athymic nude mice. Tumors were grown to at least 250mm3. Tumor tissue was mic...

ORGANISM(S): Homo sapiens

2014-01-09 | E-GEOD-35351 | biostudies-arrayexpress

The effect of FOXO3 knockdown and PDHA1 knockdown on PDAC cell line Panc-1

Little is known about the role of FOXO3 and PDHA1 in PDAC. We performed microarrays to revealed the transcriptional change of a human pancreatic ductal adenocarcinoma (PDCA) cell line (Panc -1) to scr-siRNA, FOXO3-siRNA and PDHA1-siRNA in order to provide insight into the role of PDHA1 and FOXO3 in...

ORGANISM(S): Homo sapiens

2016-09-01 | E-GEOD-66404 | biostudies-arrayexpress

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