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MetabolomicsMetabolomic Profiles of Pancreatic β-Cells and Islets Exposed to Arsenic, part I β-Cells
Not available
ORGANISM(S): Mus musculus 
ST001266 | MetabolomicsWorkbench
MetabolomicsMetabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids

Application of mass spectrometry enables the detection of metabolic differences between organisms with different nutritional settings. Divergence in the metabolic fingerprints of rat pancreatic INS-1 β-cells were systematically captured with regard to 10 individual essential amino acid (EAA) avai...

2022-05-24 | MTBLS3963 | MetaboLights
MetabolomicsMetabolomic Profiles of Pancreatic β-Cells and Islets Exposed to Arsenic, Islets (part-II)
Not available
ORGANISM(S): Mus musculus 
ST001314 | MetabolomicsWorkbench
ProteomicsQuantitative proteomics of human pancreatic beta cells
Outline: using label-free alternate-scanning LC-MS/MS, we compared the proteomic architecture of core functional pathways in pancreatic beta cells of human origin. Results: we quantified the relative molar abundance of 707 proteins mainly composed of functional pathways of metabolism, protein synthe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082882 | MassIVE
TranscriptomicsNova1 is a master regulator of alternative splicing in pancreatic beta cells
Alternative splicing (AS) is a fundamental mechanism for the regulation of gene expression. It affects more than 90% of human genes but its role in the regulation of pancreatic beta cells, the producers of insulin, remains unknown. Our recently published data indicated that the M-bM-^@M-^\neuron spe...
ORGANISM(S): Rattus norvegicus 
2014-10-01 | E-GEOD-59633 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of mouse pancreatic beta-cells, embryonic stem cells and 10 other normal adult tissues.
To gain insights into how pancreatic beta-cells are programmed in vivo, we profiled key histone methylations (H3K4/K27me3) in embryonic stem cells, multipotent progenitors of the nascent embryonic pancreas, purified beta-cells, and 10 other adult tissues (all under normal, untreated conditions). For...
ORGANISM(S): Mus musculus 
2010-03-19 | E-TABM-877 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of mouse pancreatic beta-cells.
To gain insights into how pancreatic beta-cells are programmed in vivo, we profiled key histone methylations (H3K4/K27me3) in embryonic stem cells, multipotent progenitors of the nascent embryonic pancreas, purified beta-cells, and 10 other adult tissues (all under normal, untreated conditions). For...
ORGANISM(S): Mus musculus 
2010-03-19 | E-TABM-906 | biostudies-arrayexpress
TranscriptomicsProtective unfolded protein response in human pancreatic beta cells transplanted into mice
Islet transplantation exposes beta cells to mild hyperglycemia and to the abnormal environment of the transplant site. These conditions may affect beta cells and induce the expression of genes involved in beta cell damage. Gene expression profile of human beta cells exposed to mild hyperglycemia by ...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-22097 | biostudies-arrayexpress
ModelsJiang2007 - GSIS system, Pancreatic Beta Cells
Jiang2007 - GSIS system, Pancreatic Beta Cells Description of a core kinetic model of the glucose-stimulated insulin secretion system (GSIS) in pancreatic beta cells. This model is described in the article: A kinetic core model of the glucose-stimula...
2024-09-02 | BIOMD0000000239 | BioModels
GenomicsChIP-seq analysis of RARB enrichment in SUIT2 pancreatic cancer cells
The aim of the experiment was to identify genome wide binding sites for retinoic acid receptor beta (RARB) in RARB agonist treated human metastatic pancreatic ductal adenocarcinoma cells (SUIT2). Datasets are prsented for the ChIP-seq analysis for SUIT2 cells after 72 h treatment with either DMSO (v...
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-12792 | biostudies-arrayexpress
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