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TranscriptomicsAcceSssIble Assay to Study the Chomatin Accessibility and DNA Methylation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-38858 | biostudies-arrayexpress
TranscriptomicsAcceSssIble: an array-based assay for the study of chromatin accessibility and DNA methylation using the CpG methyltransferase SssI
Analysis of nucleosome positioning and chromatin state by using CpG methyltransferase M.SssI to methylate nuclei. Unmethylated regions that gain methylation (low to high beta value) are known to be accessible and nucleosome depleted. Intact nuclei are harvested from cells and treated with M.SssI. DN...
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-36580 | biostudies-arrayexpress
TranscriptomicsFunctional DNA methylation is accompanied by chromatin accessibility [gene expression]
Analysis of nucleosome positioning and chromatin state by using CpG methyltransferase M.SssI to methylate nuclei. Unmethylated regions that gain methylation (low to high beta value) are known to be accessible and nucleosome depleted. Method used to study changes after epigenetic drug treatments iden...
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-43852 | biostudies-arrayexpress
TranscriptomicsFunctional DNA methylation is accompanied by chromatin accessibility [methylation]
Analysis of nucleosome positioning and chromatin state by using CpG methyltransferase M.SssI to methylate nuclei. Unmethylated regions that gain methylation (low to high beta value) are known to be accessible and nucleosome depleted. Method used to study changes after epigenetic drug treatments iden...
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-43851 | biostudies-arrayexpress
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