Sort   by:  
 Page size 
TranscriptomicsTranscriptomic profile of human mesenchymal stem cells after statins treatment
Analysis of the effect of all available statins (atorvastatin, lovastatin, simvastatin, fluvastatin, cerivastatin, pravastatin, rosuvastatin, and pitavastatin) on the expression of genes in human cell cultures to investigate potential anti-inflammatory effect during COVID-19 disease. Transcription p...
ORGANISM(S): Homo sapiens 
2024-01-01 | E-MTAB-11579 | biostudies-arrayexpress
TranscriptomicsRNA-seq of of dermal fibroblasts
Dermal fibroblasts from human, rhesus macaque, mouse and rat, stimulated with dsRNA (poly I:C), interferon and controls.
The innate immune response - the expression programme that is initiated once a pathogen is sensed - is known to be variable among responding cells, as well as to rapidly evolve...
ORGANISM(S): Mus musculus 
2018-07-06 | E-MTAB-5919 | biostudies-arrayexpress
TranscriptomicsPaired scRNAseq of the and non-hematopoietic and the immune microenvironment of aspirates from newly diagnosed Multiple Myeloma patients versus non-cancer controls
By generating a paired single cell RNA-sequencing database of the tumor niche from 10 newly diagnosed MM patients, we created a unique dataset allowing the in-depth analyses of stromal-immune interactions within the tumor microenvironment. Using this database, we identified the presence of inflammat...
ORGANISM(S): Homo sapiens 
2020-09-30 | E-MTAB-9139 | biostudies-arrayexpress
TranscriptomicsAn IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma
Neutrophils are the most abundant nucleated cell type in the bone marrow. A pro-tumor bias in this cell type may have implications for bone-marrow residing malignancies, such as multiple myeloma. Here, we generated single cell transcriptomic overviews of the entire myeloid compartment, including the...
ORGANISM(S): Homo sapiens 
2023-03-31 | E-MTAB-12760 | biostudies-arrayexpress
Sort   by:  
 Page size